DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1632 and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	372	Identity:	74/372 - (19%)
Similarity:	119/372 - (31%)	Gaps:	139/372 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   689 CGVQSALFNAKQHLSLPKMSA-PGDWPWLVALFREDIHVCDGTLITQDWVLTTEGCFQGQPRAT- 751
            ||.:..|....:...:..|.| ||||||.|:|...::|.|.|.||:..||||...||:..|...
Mouse   172 CGARPDLITLSEERIIGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCFKSYPNPQY 236

  Fly   752 WMAIVGAVRLSAKAPWTQRRRIIGMI-----KSPVEGSTAALVRLETPVSYSDHVRPICLPDALQ 811
            |.|..|...:|.:.    |.|:..::     .|....:..|:|:|:..|::|.::..:|||.|.|
Mouse   237 WTATFGVSTMSPRL----RVRVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQ 297

  Fly   812 RRLLQQPPAQRRSHVPVAERLEGQLVSQQRSRLSQENQQFFLIPSQEQQDSSTENQGDEDQDEQE 876
            .                                        :||.
Mouse   298 N----------------------------------------IIPG-------------------- 302

  Fly   877 DHFGGESAASYMPKAEALHQELDGYPLPDHAPQVNYYSSSSTVTSSSTAARIATKAPILAAVPAA 941
                                            .|.|.:...::|....|.....:..:  .:.::
Mouse   303 --------------------------------SVAYVTGWGSLTYGGNAVTNLRQGEV--RIISS 333

  Fly   942 QEQIWTNCNT-LGWSRQRDHLQRVQLKMGDMAPCENVSIATVNSMCMEATYQKYDCTQEEYSGAP 1005
            :|     ||| .|:|             |.:.|         ..:|........|..|.:..|..
Mouse   334 EE-----CNTPAGYS-------------GSVLP---------GMLCAGMRSGAVDACQGDSGGPL 371

  Fly  1006 VQCLIPGTNQWALIGVSSWRIACG-PTGVERPRMYDKIASNAAWIRE 1051
            ||  ......|.::|:.||...|| |   .:|.:|.::.:...|||:
Mouse   372 VQ--EDSRRLWFVVGIVSWGYQCGLP---NKPGVYTRVTAYRNWIRQ 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450	36/107 (34%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	68/355 (19%)
		Tryp_SPc	186..414	CDD:238113	71/358 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834060
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930