DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and mom-5

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001300437.1	Gene:	mom-5 / 172856	WormBaseID:	WBGene00003397	Length:	570	Species:	Caenorhabditis elegans

Alignment Length:	162	Identity:	44/162 - (27%)
Similarity:	64/162 - (39%)	Gaps:	31/162 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 SSSPLGGHDETTEPVVTTTPAPPRRCSPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRE 424
            |.|.:.|...|            |:|..:.:..|:.:.||.|.:||||||.:..:....:..|..
Worm    24 SISSMNGFSTT------------RKCEHITIPMCKNLDYNQTVFPNLLGHTTQSEAGPAIAQFNP 76

  Fly   425 LVDGECHREAYDFVCRLLQPPCDTHGSDLQPTPGQICREYCESFMAGC-------GGRLPQRFRQ 482
            |:..:|..:...|:|.:..|.|......:||     |||.|.|...||       |.:.|.:
Worm    77 LIKVKCSEDIRLFLCTVYAPVCTVLEKPIQP-----CRELCLSAKNGCESLMKKFGFQWPDQ--- 133

  Fly   483 FFDCERFPESTGTQSCHQKPHCVSDMQSNVQS 514
             .||.:||.   |..|..|....|....|.:|
Worm   134 -LDCNKFPV---TDLCVGKNSSESSNSKNYRS 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	35/124 (28%)
		PRKCSH-like	<503..>582	CDD:193472	3/12 (25%)
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450
mom-5	NP_001300437.1	CRD_FZ1_like	35..147	CDD:143567	36/123 (29%)
		7tmF_Frizzled_SMO	219..550	CDD:320089
		TM helix 1	228..253	CDD:320089
		TM helix 2	262..282	CDD:320089
		TM helix 3	312..338	CDD:320089
		TM helix 4	355..371	CDD:320089
		TM helix 5	393..422	CDD:320089
		TM helix 6	446..473	CDD:320089
		TM helix 7	512..537	CDD:320089
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810