Protein Alignment CG1632 and Fzd3

DIOPT Version :9

• Sequence 1: NP_001245577.1
• Gene: CG1632 / 31763
• FlyBaseID: FBgn0030027
• Length: 1056
• Species: Drosophila melanogaster
• Sequence 2: NP_067433.1
• Gene: Fzd3 / 14365
• MGIID: 108476
• Length: 666
• Species: Mus musculus
• Alignment Length: 229
• Identity: 55/229 - (24%)
• Similarity: 84/229 - (36%)
• Gaps: 63/229 - (27%)

  Fly   364 LGGHDETTEPVVTTTPAPPRRCSPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDG 428
            :|||...:             |.|:.|..|:.:.||.|..||||.|...:..|..:..|..:|:.
Mouse    20 IGGHSLFS-------------CEPITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNL 71

  Fly   429 ECHREAYDFVCRLLQPPCDTHGSDLQPTPGQICREYCESFMAGCGGRLPQRF----RQFFDCERF 489
            :|.|:...|:|.|..|.|..:|....|     ||..|:...:.| .:|.:.|    .:..:|.||
Mouse    72 DCSRDFRPFLCALYAPICMEYGRVTLP-----CRRLCQRAYSEC-SKLMEMFGVPWPEDMECSRF 130

  Fly   490 PESTGTQSCHQKPHCVSDMQSNVQSPRLCD-----GYADCPDLSDERSCAFCSPNALYCG----- 544
            |:      | .:|:           |||.|     ...:...::.:|...|..|..|...
Mouse   131 PD------C-DEPY-----------PRLVDLNLVGDPTEGAPVAVQRDYGFWCPRELKIDPDLGY 177

  Fly   545 ---RGRACVPRKARCDGKADCPDGADEKDCLSIA 575
               ..|.|.|         .||:....::.||.|
Mouse   178 SFLHVRDCSP---------PCPNMYFRREELSFA 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	35/121 (29%)
		PRKCSH-like	<503..>582	CDD:193472	16/86 (19%)
		LDLa	536..571	CDD:238060	7/42 (17%)
		Tryp_SPc	708..>809	CDD:304450
Fzd3	NP_067433.1	CRD_FZ3	24..150	CDD:143558	40/162 (25%)
		Frizzled	193..512	CDD:279827	3/10 (30%)
		Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250	502..507
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	538..666

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900