DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1632 and Cfi

DIOPT Version :9

Sequence 1:NP_001245577.1 Gene:CG1632 / 31763 FlyBaseID:FBgn0030027 Length:1056 Species:Drosophila melanogaster
Sequence 2:NP_031712.2 Gene:Cfi / 12630 MGIID:105937 Length:603 Species:Mus musculus


Alignment Length:582 Identity:120/582 - (20%)
Similarity:173/582 - (29%) Gaps:239/582 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   489 FPESTGTQSCHQKPHCVSDMQSNVQSPRLCDGYADCPDLSDERSCAFCSPNALYCGRGRACVPRK 553
            ||.|...|       ||:.  .::...:.|:|..||.|.|||..|..|..||..|..| .|:|.:
Mouse   226 FPTSLSFQ-------CVNG--KHIPQEKACNGVNDCGDQSDELCCKGCRGNASLCKSG-VCIPDQ 280

  Fly   554 ARCDGKADCPDGADEKDCLSIAPLAADLLQPEPLVPYLSRFHSAGYAVFSEKGVVGKLCAEGLEG 618
            .:|:|:.||..|.||..|      ..|..|..|                  ||:     |...:|
Mouse   281 YKCNGEVDCITGEDESRC------EEDRQQNIP------------------KGL-----ARSAQG 316

  Fly   619 DAKLVVRQTVSESLCKSLGYESVEIFDVQNDTERLNDYVRVLDPHAPEISFIRTHCPRRQVLYVG 683
            :|::...:|              |:.....|.||..               |::..|:       
Mouse   317 EAEIETEET--------------EMLTPGMDNERKR---------------IKSLLPK------- 345

  Fly   684 CGELRCGVQSALFNAKQHLSLPKMSAPGDWPWLVALFREDIHVCDGTLITQDWVLTTEGCFQGQP 748
               |.|||:......::.:...|.:..||:||.||:.......|.|..|...|:||...|     
Mouse   346 ---LSCGVKRNTHTRRKRVIGGKPANVGDYPWQVAIKDGQRITCGGIYIGGCWILTAAHC----- 402

  Fly   749 RATWMAIVGAVRLSAKAPWTQRRRIIGMIKSPVEGSTAALVRLETPVSYSDHVRPICLPDALQRR 813
                   |...|..:...||                  ||:         |.::|          
Mouse   403 -------VRPSRAHSYQVWT------------------ALL---------DWLKP---------- 423

  Fly   814 LLQQPPAQRRSHVPVAERLEGQLVSQQRSRLSQENQQFFLIPSQEQQDSSTENQGDEDQDEQEDH 878
             ..|...|....|.|.|:..|...                             |.|....|.:.|
Mouse   424 -NSQLGIQTVKRVIVHEKYNGATF-----------------------------QNDIALIEMKMH 458

  Fly   879 FGGESAASYMPKAEALHQELDGYPLPDHAPQVNYYSSSSTVTSSSTAARIATKAPILAAVPAAQE 943
            .|         |.|.        .||:..|                           |.||    
Mouse   459 TG---------KKEC--------ELPNSVP---------------------------ACVP---- 475

  Fly   944 QIWT--------NCNTLGWSRQRDHLQRVQLKMGDMAPCENVSIATVNSMCMEATYQK------- 993
              |:        .|...||.|.:|:.:...|:.|::....|.|     ....:..|:|       
Mouse   476 --WSPYLFQPNDRCIISGWGRGKDNQKVYSLRWGEVDLIGNCS-----QFYPDRYYEKEMQCAGT 533

  Fly   994 ----YDCTQEEYSGAPVQC--LIPGTNQWALIGVSSWRIACGPTGVERPRMYDKIASNAAWI 1049
                .|..:.: ||.|:.|  :...|..|   |:.||...||..  |.|.:|.::|:...||
Mouse   534 RDGSIDACKGD-SGGPLVCEDINNVTYVW---GIVSWGENCGKP--EFPGVYTRVANYFDWI 589

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1632NP_001245577.1 SEA 232..327 CDD:279699
CRD_FZ 384..502 CDD:143549 4/12 (33%)
PRKCSH-like <503..>582 CDD:193472 27/78 (35%)
LDLa 536..571 CDD:238060 14/34 (41%)
Tryp_SPc 708..>809 CDD:304450 21/100 (21%)
CfiNP_031712.2 FIMAC 46..111 CDD:214493
SR 117..220 CDD:214555
SRCR 122..219 CDD:278931
LDLa 232..261 CDD:238060 11/37 (30%)
LDLa 264..298 CDD:294076 14/34 (41%)
Tryp_SPc 360..589 CDD:214473 69/368 (19%)
Tryp_SPc 361..592 CDD:238113 71/369 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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