DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and sfrp5

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_571933.1	Gene:	sfrp5 / 117510	ZFINID:	ZDB-GENE-011108-2	Length:	310	Species:	Danio rerio

Alignment Length:	153	Identity:	36/153 - (23%)
Similarity:	55/153 - (35%)	Gaps:	32/153 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   387 PLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQPPCDTHGS 451
            |.:|..|..|||.....||||.|.:..::.:....:..|:...||.:...|:|.|..|.|
Zfish    56 PADLRLCYNVGYKKMRLPNLLDHETMPEVKQQAGSWVPLLAKRCHADTQVFLCSLFAPVC----- 115

  Fly   452 DLQPTPGQICREYCESFMAGC-------GGRLPQRFRQFFDCERFP--------------ESTGT 495
              ...|...||..||:....|       |...|    :...||:||              .:|.|
Zfish   116 --LDRPIYPCRSLCEAVRDSCAPVMETYGFPWP----EMLQCEKFPIDNDLCIPMQFSAGHATQT 174

  Fly   496 QSCHQKPHCVSDMQSNVQSPRLC 518
            ......|.|.::::::......|
Zfish   175 PVSKVCPPCDNELKADTIMEHYC 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	33/135 (24%)
		PRKCSH-like	<503..>582	CDD:193472	2/16 (13%)
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450
sfrp5	NP_571933.1	CRD_SFRP5	46..172	CDD:143553	31/126 (25%)
sfrp5	NP_571933.1	NTR_Sfrp1_like	177..302	CDD:239635	3/21 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900