DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and mfrp

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	XP_009289590.1	Gene:	mfrp / 101885305	ZFINID:	ZDB-GENE-160728-150	Length:	572	Species:	Danio rerio

Alignment Length:	311	Identity:	67/311 - (21%)
Similarity:	110/311 - (35%)	Gaps:	92/311 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 PEPLPDRVFRGRFMVLNDKWSMELANQNSMRFQHKARDYRERINLTLRRSDLREAYEGSEIL--- 286
            |:|.|.:......:.:.|...:.|:.||   |..:|:|        :.:.|..|.|:|:|..
Zfish   314 PKPYPHQQMCTWQISVEDGQVIRLSFQN---FSLEAQD--------VCKFDYVEVYDGAETALGR 367

  Fly   287 ----ALDGSEDNNNIVVHFNMIFDPYAGLVSSGDLLALFHEEMTQPPQQRRHFANMTVDVASLSI 347
                ||.....::..|:  .::|....|:..|| ..|.|.                     ::|:
Zfish   368 YCGSALPPDLTSSGPVL--TVVFVADEGVADSG-FYASFQ---------------------AISL 408

  Fly   348 KETTGLIEEPIMSSSPLG-----------------GHDE-----TTEPVVTTTPAPPRRCSPLEL 390
            .|.|.   .|...:.|.|                 |.||     :|.|..|::      |..:::
Zfish   409 SERTC---SPAQFACPTGECLHQDWLCDGWSDCADGADEHHCMNSTYPPFTSS------CELIQV 464

  Fly   391 SYCRQVGYNITTYPNL-LGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQPPCDTHGSDLQ 454
            ..||.:.||:|::||: |..:...:.|..:..:|.|||..|.......||.:..|.|......|
Zfish   465 EMCRDLSYNLTSFPNIWLSLSDQREAASILHKYRVLVDLPCFESFRQLVCGMFLPRCSPQSGVL- 528

  Fly   455 PTPGQICREYCESFMAGCGGRL-------PQRFRQFFDCERFPESTGTQSC 498
                |:|:..|.:....|...|       |      |:|...|:|.....|
Zfish   529 ----QLCQSVCSTAELQCSPALSLFSLNWP------FNCLLLPDSHDPMEC 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699	21/101 (21%)
		CRD_FZ	384..502	CDD:143549	31/123 (25%)
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450
mfrp	XP_009289590.1	CUB	138..248	CDD:238001
		LDLa	256..290	CDD:238060
		CUB	297..405	CDD:238001	24/125 (19%)
		LDLa	413..447	CDD:238060	6/36 (17%)
		Fz	459..563	CDD:279700	29/114 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900