DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and tmprss13

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	XP_002932950.2	Gene:	tmprss13 / 100491822	XenbaseID:	XB-GENE-940757	Length:	462	Species:	Xenopus tropicalis

Alignment Length:	531	Identity:	105/531 - (19%)
Similarity:	167/531 - (31%)	Gaps:	201/531 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   549 CVPRKARCDGKADCPDGADEKDCLSIAPLAADLLQPEPLVPYLSRFHSAGYAVFSEKGVVGKLCA 613
            |:.....|:|.|:|..|.||..|       |..|....:|..:||         .::.:...:|.
Frog   101 CLSNVTLCNGVAECERGGDEMGC-------ARFLWDNSMVEVMSR---------KKENLWLPVCY 149

  Fly   614 EGLEGDAKLVVRQTVSESLCKSLGYE----SVEIFDVQNDTERLNDYVRVLDPHAPEI------S 668
            .....|....|        |:..|:|    :..::...|:.           .|:..|      |
Frog   150 NEYSSDFPSFV--------CQRYGFEGTPATAPVYFASNEA-----------LHSTGIQNTIQGS 195

  Fly   669 FIRTHCPRRQVLYVGCGELRCGVQSALFNAKQHLSLPKMSAP-GDWPWLVALFRED----IHVCD 728
            ...|.|...|.|.:.|  |.||.:.|      :..:..:||. ||:||.|:|.:..    .|||.
Frog   196 LQSTTCANGQYLSLRC--LDCGKRMA------NRIIGGVSAKLGDYPWQVSLHQRAGNRFAHVCG 252

  Fly   729 GTLITQDWVLTTEGCFQG--QPRATWMAIVGAV---RLSAKAPWTQRRRIIGMI------KSPVE 782
            ||:|...||.|...|||.  .| |.|....|.:   .|:|       ...:.:|      .|..:
Frog   253 GTIINNKWVATATHCFQETVDP-ANWRVYAGIINQHNLNA-------MHTVTVIVRNENYNSDTD 309

  Fly   783 GSTAALVRLETPVSYSDHVRPICLPDALQRRLLQQPPAQRRSHVPVAERLEGQLVSQQRSRLSQE 847
            ....||::::.|..::..::|.|||                                      ..
Frog   310 DFDMALMKMKQPFIFTAAIQPACLP--------------------------------------MM 336

  Fly   848 NQQFFLIPSQEQQDSSTENQGDEDQDEQEDHFGGESAASYMPKAEALHQELDGYPLPDHAPQVNY 912
            ||.|                             |::...:          :.|:
Frog   337 NQNF-----------------------------GQNDICF----------ISGF----------- 351

  Fly   913 YSSSSTVTSSSTAARIATKAPILAAVPAAQEQIWTNCNTLGWSRQRDHLQRVQLKMGDMAPCENV 977
               ..|:.||...::...:|.: ..:|.:.      ||            :|.:..|.:.|
Frog   352 ---GKTIQSSDEGSQYLMQAQV-HVIPTSV------CN------------KVNVYNGAITP---- 390

  Fly   978 SIATVNSMCMEATYQKYDCTQEEYSGAPVQCLIPGTNQWALIGVSSWRIACGPTGVERPRMYDKI 1042
                 ..||......:.|..|.: ||.|:.|...|.  |.|.||:||...||.  ..:|.:|..:
Frog   391 -----RMMCAGYLQGQIDSCQGD-SGGPLVCQQGGI--WYLAGVTSWGSGCGQ--ANKPGVYSNV 445

  Fly  1043 ASNAAWIRETI 1053
            .:...||.:.|
Frog   446 NAFLQWIYKQI 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472	10/32 (31%)
		LDLa	536..571	CDD:238060	8/21 (38%)
		Tryp_SPc	708..>809	CDD:304450	35/116 (30%)
tmprss13	XP_002932950.2	SRCR_2	128..217	CDD:382996	21/118 (18%)
tmprss13	XP_002932950.2	Tryp_SPc	222..455	CDD:238113	71/364 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910