DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1632 and tmprss15

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	XP_031752048.1	Gene:	tmprss15 / 100490249	XenbaseID:	XB-GENE-999987	Length:	994	Species:	Xenopus tropicalis

Alignment Length:	816	Identity:	149/816 - (18%)
Similarity:	251/816 - (30%)	Gaps:	337/816 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 FANMTVDV--------------ASLSIKETTGLIE--EPIM-----------------SSSPLGG 366
            |||.|..:              ..:::.||:|.:.  |.|.                 |.:..|.
Frog   418 FANSTETIIFQKEGNYGPSWNYGQVTLSETSGTVVAFEAIQNQRFGDIAIDDIGLFPGSCNESGF 482

  Fly   367 HDETTEPVVTTTPAPPRRC-SPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGEC 430
            .:.|..|.|.||...|..| .|.|| :...|.::...||.     :|..||.
Frog   483 PEPTRVPTVPTTALLPSDCGGPTEL-WEPNVTFHSANYPQ-----NYPNLAS------------- 528

  Fly   431 HREAYDFVCRLLQPPCDTHGSDLQPTPGQICREYCESFMAGCGGRLPQRFRQFFDCE-------- 487
                                              |..::....|:..|...|.|:.|
Frog   529 ----------------------------------CVWYLNAAPGKNIQLHFQVFNLENIYDVVEI 559

  Fly   488 ---RFPES------TGTQSCHQKPHCVSDMQSNVQSPRLCDGYADCPDLSDERSCAF-------- 535
               |.|:|      ||:..       |.|:.|...:..:   |.    .||....|.
Frog   560 RDGRGPDSLLLAVYTGSAP-------VKDVFSTTSAMSV---YF----TSDSTGTAKGFLANYTT 610

  Fly   536 ---------CSPNALYCGRGRACVPRKARCDGKADCPDGADEKDCL-----SIAPLAADLLQPEP 586
                     |:..:..||.|. |:|..|.||...||.||.||:.|:     |::.|....:|
Frog   611 GLRLGMPEPCNSTSFQCGSGE-CIPNTAVCDKHRDCDDGTDERHCVRLFNSSMSGLVQFKVQ--- 671

  Fly   587 LVPYLSRFHSAGYAVFSEKGVVGKLCAEGLEGDAKLVVRQTVSESLCKSLGYESVEIFDVQNDTE 651
                 |.:|:|              |.:....|        :|..:|..||..:|.:..... :|
Frog   672 -----SEWHTA--------------CIDHWNED--------ISNDICHRLGLGNVNLTSAVL-SE 708

  Fly   652 RLNDYVRVLDPHAPEISFIRT-HCPRRQVLYVGCGELRCGVQSALFNAKQHLSLPKMSAPGDWPW 715
            ....:|.::......:|.:.: .|..:.|:::.|.:..||.:.....:...:.....:|.|.|||
Frog   709 GNGPFVTLIQVEDGSLSLLPSDQCANQSVIHIQCQQRECGKRLVPIKSGSKIVGGSDAALGAWPW 773

  Fly   716 LVALFREDIHVCDGTLITQDWVLTTEGCFQGQ---PRATWMAIVGA-VRLSAKAPWTQRRRIIGM 776
            :|:|:..|...|..:|:.|:|:::...|..|:   | :.|.|.:|. ..|:...|....:.|..:
Frog   774 IVSLYYNDRQTCGASLVNQEWLVSAAHCVYGRNLIP-SNWKARLGLHTNLNLTQPQIATQMIDQI 837

  Fly   777 IKSP-----VEGSTAALVRLETPVSYSDHVRPICLPDALQRRLLQQPPAQRRSHVPVAERLEGQL 836
            :.:|     .:.|...::.|:..|:|||:::|||||:.
Frog   838 VINPQYNRRTKDSDIVMMHLQFKVNYSDYIQPICLPET--------------------------- 875

  Fly   837 VSQQRSRLSQENQQFFLIPSQEQQDSSTENQGDEDQDEQEDHFGGESAASYMPKAEALHQELDGY 901
                       :|:|
Frog   876 -----------DQEF-------------------------------------------------- 879

  Fly   902 PLPDHAPQVNYYSSSSTVTSSSTAARIATKAPILAAVPAAQEQIWTNCNTLGWSRQR------DH 960
                                                      .:..||:..||.|.:      :.
Frog   880 ------------------------------------------SVGINCSIAGWGRTQSGGPVPNI 902

  Fly   961 LQRVQLKMGDMAPCE------NVSIATVNSMCMEATYQK--YDCTQEEYSGAPVQCLIPGTNQWA 1017
            ||..::.:.....|:      |:   |.|.:|  ..|::  .|..|.: ||.|:.|  ...|:|.
Frog   903 LQEAEIPLISNHKCQQQMPEYNI---TDNMVC--GGYEEGGIDTCQGD-SGGPMMC--QQNNEWF 959

  Fly  1018 LIGVSSWRIACGPTGVERPRMYDKIASNAAWIRETI 1053
            |:||:|:...|...  .||.:|.::.....||:..|
Frog   960 LVGVTSFGYGCAQP--SRPGVYVRVTEFTNWIKSFI 993

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	21/135 (16%)
		PRKCSH-like	<503..>582	CDD:193472	25/100 (25%)
		LDLa	536..571	CDD:238060	15/34 (44%)
		Tryp_SPc	708..>809	CDD:304450	33/109 (30%)
tmprss15	XP_031752048.1	SEA	36..>103	CDD:396113
		LDLa	157..190	CDD:197566
		CUB	199..305	CDD:238001
		MAM	321..478	CDD:395504	10/59 (17%)
		CUB	501..608	CDD:395345	28/173 (16%)
		LDLa	620..654	CDD:238060	15/34 (44%)
		SR	655..746	CDD:214555	19/121 (16%)
		Tryp_SPc	760..991	CDD:238113	66/371 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910