DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and clcn2

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	XP_002935192.2	Gene:	clcn2 / 100488889	XenbaseID:	XB-GENE-494657	Length:	882	Species:	Xenopus tropicalis

Alignment Length:	188	Identity:	45/188 - (23%)
Similarity:	73/188 - (38%)	Gaps:	52/188 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   879 FG---GESAASYMPKAEALHQELDGYPL-PDHAPQVNYYSSSSTVTSS-STA-------ARIATK 931
            ||   |||.|::.|  :.:|.:...|.: |.....|...:.|..||.: |||       .:|:..
Frog   463 FGRLVGESMAAWFP--DGIHTDGSTYRIVPGGYAVVGAAALSGAVTHTVSTAVIVFELTGQISHI 525

  Fly   932 APILAAVPAA-------QEQIWTN---------CNTLGWSRQRDHLQRVQLKMGDMAPCENVSIA 980
            .|::.||..|       |..::.:         ...|||..|..:..||:..|     ..|:...
Frog   526 LPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLPELGWGHQEKYNVRVEDIM-----LRNIPFV 585

  Fly   981 TVNSMCMEATYQKYDCTQEEYSGAPVQCLIPGTNQWALIGVSSWRIACGPTGVERPRM 1038
            |:||        ||...||..:...::||       ||:..:...|..|  .::|.::
Frog   586 TLNS--------KYRDLQELLTNCHLKCL-------ALVETAESMILLG--SIDRSQL 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450
clcn2	XP_002935192.2	ClC_1_like	84..561	CDD:239655	23/99 (23%)
		CBS_pair_voltage-gated_CLC_euk_bac	<774..824	CDD:341367
		CBS repeat	781..823	CDD:341367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165163401
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930