Protein Alignment ND-75 and ND-75

DIOPT Version :10

• Sequence 1: NP_511083.1
• Gene: ND-75 / 31762
• FlyBaseID: FBgn0017566
• Length: 731
• Species: Drosophila melanogaster
• Sequence 2: XP_321442.4
• Gene: ND-75 / 1281520
• VectorBaseID: AGAMI1_005497
• Length: 726
• Species: Anopheles gambiae
• Alignment Length: 734
• Identity: 526/734 - (71%)
• Similarity: 609/734 - (82%)
• Gaps: 19/734 - (2%)

  Fly     1 MIRAPLVKALGALGS--PTHQMASRAVRTSAMVAQTPAKAPEKIEVFVDDIPVQVVPGTTVLQAA 63
            |:|.|:.:|| |||:  |...:    ||||   |.||||.||||||||||.||.|.|||||||||
Mosquito     1 MLRVPVTRAL-ALGARFPVQTI----VRTS---ATTPAKVPEKIEVFVDDQPVMVDPGTTVLQAA 57

  Fly    64 AQIGVEIPRFCYHERLAVAGNCRMCLVEVEKSPKPVAACAMPVMKGWRIKTNSDLTRKAREGVME 128
            ||:||||||||||||||||||||||||||||||||||||||||||||||||||::||||||||||
Mosquito    58 AQVGVEIPRFCYHERLAVAGNCRMCLVEVEKSPKPVAACAMPVMKGWRIKTNSEMTRKAREGVME 122

  Fly   129 FLLMNHPLDCPICDQGGECDLQDQAMAFGSDRSRFTDINYTGKRAVEDKDIGPLVKTIMTRCIHC 193
            ||||||||||||||||||||||||||||||||||||||::||||||||||||||:||||||||||
Mosquito   123 FLLMNHPLDCPICDQGGECDLQDQAMAFGSDRSRFTDIHHTGKRAVEDKDIGPLIKTIMTRCIHC 187

  Fly   194 TRCVRFASEIAGVDDLGTTGRGNDMQIGTYVEKLFLTELSGNVIDLCPVGALTNKPYSFVARPWE 258
            |||:|||||:|||||||||||||||||||||||.||:||||||||||||||||||||||||||||
Mosquito   188 TRCIRFASEVAGVDDLGTTGRGNDMQIGTYVEKFFLSELSGNVIDLCPVGALTNKPYSFVARPWE 252

  Fly   259 IRKVSSIDVLDAVGSNIVVSTRTNEVLRILPRENEDVNEEWLADKSRFACDGLKRQRLVAPMVRM 323
            |||:.|||||||:||||||||||.||||||||||:::|||||:|||||||||||||||:|||:|.
Mosquito   253 IRKIESIDVLDALGSNIVVSTRTGEVLRILPRENDEINEEWLSDKSRFACDGLKRQRLIAPMLRN 317

  Fly   324 PNGELQAVEWEGALIAVAKAIKAA-GGQIAGISGQLADLEAQVALKDLLNRLGSEVVATEQGF-- 385
            |:|||:|||||.|||.:|:|::.| .|::|.::|.|.|.|:.|||||||||||||.:.|||.|
Mosquito   318 PSGELEAVEWESALITIAQALRGAPKGKVAAVAGGLVDAESLVALKDLLNRLGSETLCTEQKFPT 382

  Fly   386 IAGGTDNRANYLLNSTIAGLEEADAVLLVGTNPRYEAPLVNTRLRKAYVHNELQIASIGPKIDLS 450
            ...|||.|::|||||:||..||||.||||||||||||||:||||||.|:||:..||.||||::||
Mosquito   383 DGSGTDLRSSYLLNSSIAACEEADLVLLVGTNPRYEAPLLNTRLRKGYIHNDQNIALIGPKVNLS 447

  Fly   451 YDHENLGADAALVKDVCSGAHAFSKVLEGAKKPAIIIGADLLERADGAAIHATVAEYCKKLK--K 513
            ||:|:||:|.:|::|:.:|.|.|:|.|:.||||.||:||:.|.|.||.:....:..:...|.  .
Mosquito   448 YDYEHLGSDTSLIRDIANGHHPFAKKLKEAKKPLIIVGANQLARKDGTSFLTALHVFANSLSPAD 512

  Fly   514 PNWNPFNVLQTNAAQVGALDVGYKAGAQTAVKAQPKVLFLLNADAGKVTREQLPKDCFVVYIGSH 578
            .||..:|||||||||..||||||..|.:.|::|||||||||.||||.|.:|:||||||:||.|.|
Mosquito   513 KNWKVWNVLQTNAAQTAALDVGYTPGVEAALEAQPKVLFLLGADAGVVDKEKLPKDCFIVYQGHH 577

  Fly   579 GDNGASIADAVLPGAAYTEKQGIYVNTEGRPQQTLPGVSPPGMAREDWKILRALSEVVGKPLPYD 643
            ||.||.:|.|:|||||||||||.|||||||.||||..|:|||:||||||||||||||.|.|||||
Mosquito   578 GDAGAQMAHAILPGAAYTEKQGTYVNTEGRAQQTLVAVTPPGLAREDWKILRALSEVAGAPLPYD 642

  Fly   644 NLDELRNRLEDVAPHLTRLGQLEPAGDAGAAGTISKS----IGGGAIDIKLKELRDYFMTDAISR 704
            .||:||.|:||:||||.|.|:||.:.....|..:.|:    ..||.:|:..|:|.|:||||.|:|
Mosquito   643 TLDDLRTRMEDIAPHLVRYGRLEASNFFAIADALLKNSSVQFDGGKVDVVQKKLADFFMTDPITR 707

  Fly   705 ASPTMAKCISAVNKQQREN 723
            ||||||||::|..||.:.|
Mosquito   708 ASPTMAKCVTAAKKQLQAN 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ND-75	NP_511083.1	NuoG	44..632	CDD:273904	451/592 (76%)
		NADH_dhqG_C	671..712	CDD:462757	20/44 (45%)
ND-75	XP_321442.4	NuoG	38..631	CDD:273904	455/597 (76%)
		NADH_dhqG_C	673..715	CDD:462757	22/45 (49%)