Protein Alignment Trxr1 and IRC15

DIOPT Version :10

• Sequence 1: NP_727251.1
• Gene: Trxr1 / 31760
• FlyBaseID: FBgn0020653
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_015308.1
• Gene: IRC15 / 856090
• SGDID: S000005938
• Length: 499
• Species: Saccharomyces cerevisiae
• Alignment Length: 507
• Identity: 115/507 - (22%)
• Similarity: 209/507 - (41%)
• Gaps: 63/507 - (12%)

  Fly   115 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLL 179
            ||::|||.|..|...|.:|...|...||:|         .:..:||..:..|.:|.|.:...|.|
Yeast    18 YDVLVIGCGPGGFTAAMQASQAGLLTACVD---------QRASLGGAYLVDGAVPSKTLLYESYL 73

  Fly   180 GEAVHEAAAYGWNVDEK------IKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFV 238
            ...:.:...    ::::      .|.|......:::::|:.:..|.:.:|....|....|..:|.
Yeast    74 YRLLQQQEL----IEQRGTRLFPAKFDMQAAQSALKHNIEELGNVYKRELSKNNVTVYKGTAAFK 134

  Fly   239 DSHTL-LAKLKSGERTITAQTFVIAVGGRPRYPDIPG-AVEYG--ITSDDLFSLDREPGKTLVVG 299
            |.|.: :|:.......:.|:..|:|.|.  .....|| |::..  |:||...|||..|.:..::|
Yeast   135 DPHHVEIAQRGMKPFIVEAKYIVVATGS--AVIQCPGVAIDNDKIISSDKALSLDYIPSRFTIMG 197

  Fly   300 AGYIGLECAGFLKGLGYEPTVM-VRSIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEKQDD 363
            .|.||||.|.....||...|:: .:|.:.:..|.::|......::.:||.||..|.....|....
Yeast   198 GGTIGLEIACIFNNLGSRVTIVESQSEICQNMDNELASATKTLLQCQGIAFLLDTRVQLAEADAA 262

  Fly   364 GKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK--DKIPVDSQEATNVANI 426
            |:|.:...|..:.:......|.::.:|||:.|:..|::.:.|:..:.  :.:.|.:|......:|
Yeast   263 GQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLKGLDISSIGLDERDFVENVDVQTQSLLKYPHI 327

  Fly   427 YAVGDIIYGKPELTPVAVLAGRLLARRLY-----GGSTQRMDYKDVATTVFTPLEYACVGLSEED 486
            ..:||:..|     |:..|.....|.|..     .||....:.......::...:...||.:||.
Yeast   328 KPIGDVTLG-----PMLALKAEEQAIRAIQSIGCTGSDGTSNCGFPPNVLYCQPQIGWVGYTEEG 387

  Fly   487 AVKQFGADEIEVFHGYYKPTEFFIPQKSVRY-------------CYLKAVAERHGDQRVYGLHYI 538
            ..|.    .|.    |.|....|  .::|||             .::|.:.:.. |.::.|:|.|
Yeast   388 LAKA----RIP----YQKGRVLF--SQNVRYNTLLPREENTTVSPFIKVLIDSR-DMKILGVHMI 441

  Fly   539 GPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTR-LAITKRSGLDP 589
            ...|.|::...:.|:..|||.:.:......||:.:|.|.: :.:...:|..|
Yeast   442 NDDANELLSQASMAVSLGLTAHDVCKVPFPHPSLSESFKQAVQLAMANGTSP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr1	NP_727251.1	DAO	59..>160	CDD:477422	13/44 (30%)
		TGR	113..595	CDD:273624	115/507 (23%)
IRC15	NP_015308.1	Lpd	18..487	CDD:440861	113/499 (23%)