DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Trxr-1 and GR

DIOPT Version :9

Sequence 1:	NP_727251.1	Gene:	Trxr-1 / 31760	FlyBaseID:	FBgn0020653	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_191026.1	Gene:	GR / 824631	AraportID:	AT3G54660	Length:	565	Species:	Arabidopsis thaliana

Alignment Length:	494	Identity:	174/494 - (35%)
Similarity:	257/494 - (52%)	Gaps:	35/494 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 STKGGS-----YDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVG 166
            ||..|:     ||:||..||.||.|:..::.|...||..|..:....|.:..|..|||||||..|
plant    75 STDNGAESDRHYDFDLFTIGAGSGGVRASRFATSFGASAAVCELPFSTISSDTAGGVGGTCVLRG 139

  Fly   167 CIPKKLMHQASLLGEAVHEAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYI 231
            |:||||:..||.......::..:||..:.:...||..|:.:....::.:..:.:..|....|:.|
plant   140 CVPKKLLVYASKYSHEFEDSHGFGWKYETEPSHDWTTLIANKNAELQRLTGIYKNILSKANVKLI 204

  Fly   232 NGLGSFVDSHTLLAKLKSGERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTL 296
            .|.|..:|.||    :....:..|.:..:|||||||..|||||. |:.|.||....|..:|.|..
plant   205 EGRGKVIDPHT----VDVDGKIYTTRNILIAVGGRPFIPDIPGK-EFAIDSDAALDLPSKPKKIA 264

  Fly   297 VVGAGYIGLECAGFLKGLGYEPTVMVR-SIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEK 360
            :||.|||.||.||...||..|..|.:| ..||||||:.:.:.|...|..|||.|..:..|.::.|
plant   265 IVGGGYIALEFAGIFNGLNCEVHVFIRQKKVLRGFDEDVRDFVGEQMSLRGIEFHTEESPEAIIK 329

  Fly   361 QDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQKD-KIPVDSQEATNVA 424
            ..||...:|     |.:...:.:..|::|.|||....:|.|.|.||.:.|: .|.||....|:|.
plant   330 AGDGSFSLK-----TSKGTVEGFSHVMFATGRKPNTKNLGLENVGVKMAKNGAIEVDEYSQTSVP 389

  Fly   425 NIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVK 489
            :|:||||:. .:..|||||::.|..||:.|:.....:.||:.|...||:......|||:||.|::
plant   390 SIWAVGDVT-DRINLTPVALMEGGALAKTLFQNEPTKPDYRAVPCAVFSQPPIGTVGLTEEQAIE 453

  Fly   490 QFGADEIEVFHGYYKP---TEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAA 551
            |:|  :::|:...::|   |...:|.:    .::|.:...: ..:|.|:|..|..:.|:||||..
plant   454 QYG--DVDVYTSNFRPLKATLSGLPDR----VFMKLIVCAN-TNKVLGVHMCGEDSPEIIQGFGV 511

  Fly   552 ALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPT 590
            |:|:|||......|||:|||.||||    :|.|:   ||
plant   512 AVKAGLTKADFDATVGVHPTAAEEF----VTMRA---PT 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trxr-1	NP_727251.1	TGR	113..595	CDD:273624	171/483 (35%)
		NADB_Rossmann	115..>150	CDD:304358	11/34 (32%)
		Pyr_redox	294..368	CDD:278498	31/74 (42%)
		Pyr_redox_dim	468..577	CDD:280934	38/111 (34%)
GR	NP_191026.1	PLN02546	1..565	CDD:215301	174/494 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	187	1.000	Domainoid score	I973
eggNOG	1	0.900	-	-		E1_COG1249
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	264	1.000	Inparanoid score	I952
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D581771at2759
OrthoFinder	1	1.000	-	-		FOG0000578
OrthoInspector	1	1.000	-	-		mtm1060
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48105
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1089
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.970