DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Trxr-1 and GR1

DIOPT Version :9

Sequence 1:	NP_727251.1	Gene:	Trxr-1 / 31760	FlyBaseID:	FBgn0020653	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_001030756.2	Gene:	GR1 / 822003	AraportID:	AT3G24170	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	486	Identity:	176/486 - (36%)
Similarity:	261/486 - (53%)	Gaps:	21/486 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 YDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTK--WGVGGTCVNVGCIPKKLMHQ 175
            ||:||.|||.||.|:..|:.:..:||:|...:.  |...:.::  .|||||||..||:|||::..
plant    24 YDFDLFVIGAGSGGVRAARFSANHGAKVGICEL--PFHPISSEEIGGVGGTCVIRGCVPKKILVY 86

  Fly   176 ASLLGEAVHEAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDS 240
            .:..|..:.:|..|||.::||:...|.||:|...:.|..:|.:.:..|.:..|:...|.|..|..
plant    87 GATYGGELEDAKNYGWEINEKVDFTWKKLLQKKTDEILRLNNIYKRLLANAAVKLYEGEGRVVGP 151

  Fly   241 HTLLAKLKSGER-TITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIG 304
            :.:..:...|.: :.||:..:||.|.|.:.|:|||. |..||||:..||:..|.:.:|:|.|||.
plant   152 NEVEVRQIDGTKISYTAKHILIATGSRAQKPNIPGH-ELAITSDEALSLEEFPKRAIVLGGGYIA 215

  Fly   305 LECAGFLKGLGYEPTVMVR-SIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEKQDDG-KLL 367
            :|.|...:|:|....:..| .:.|||||.:|..|||.::|.||:....:|....:.|.|.| |::
plant   216 VEFASIWRGMGATVDLFFRKELPLRGFDDEMRALVARNLEGRGVNLHPQTSLTQLTKTDQGIKVI 280

  Fly   368 VKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTV-QKDKIPVDSQEATNVANIYAVGD 431
            ..:     |||.  |.|.||:|.||......|||...||.: |...:.||....||:.:|:||||
plant   281 SSH-----GEEF--VADVVLFATGRSPNTKRLNLEAVGVELDQAGAVKVDEYSRTNIPSIWAVGD 338

  Fly   432 IIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEI 496
            .. .:..|||||::.....|...:||...:.:|.:||..||.....|.||||||:||:|...| |
plant   339 AT-NRINLTPVALMEATCFANTAFGGKPTKAEYSNVACAVFCIPPLAVVGLSEEEAVEQATGD-I 401

  Fly   497 EVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINT 561
            .||...:.|.:..|..:..: ..:|.:.:...| :|.|....||.|.|::||.|.|||.|.|...
plant   402 LVFTSGFNPMKNTISGRQEK-TLMKLIVDEKSD-KVIGASMCGPDAAEIMQGIAIALKCGATKAQ 464

  Fly   562 LINTVGIHPTTAEEF-TRLAITKRSGLDPTP 591
            ..:||||||::|||| |..::|:|....|.|
plant   465 FDSTVGIHPSSAEEFVTMRSVTRRIAHKPKP 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trxr-1	NP_727251.1	TGR	113..595	CDD:273624	176/486 (36%)
		NADB_Rossmann	115..>150	CDD:304358	13/34 (38%)
		Pyr_redox	294..368	CDD:278498	27/75 (36%)
		Pyr_redox_dim	468..577	CDD:280934	45/109 (41%)
GR1	NP_001030756.2	PLN02507	1..499	CDD:215281	176/486 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	187	1.000	Domainoid score	I973
eggNOG	1	0.900	-	-		E1_COG1249
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	264	1.000	Inparanoid score	I952
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D581771at2759
OrthoFinder	1	1.000	-	-		FOG0000578
OrthoInspector	1	1.000	-	-		mtm1060
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48105
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1089
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.970