Protein Alignment Trxr1 and txnrd2.2

DIOPT Version :10

• Sequence 1: NP_727251.1
• Gene: Trxr1 / 31760
• FlyBaseID: FBgn0020653
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001340325.1
• Gene: txnrd2.2 / 798259
• ZFINID: ZDB-GENE-040914-66
• Length: 517
• Species: Danio rerio
• Alignment Length: 488
• Identity: 278/488 - (56%)
• Similarity: 352/488 - (72%)
• Gaps: 5/488 - (1%)

  Fly   111 GSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQ 175
            |.:||||:||||||.||||:|||...|.:||.||:|:|: ..|||||:|||||||||||||||||
Zfish    29 GKFDYDLVVIGGGSGGLACSKEAAQLGQKVAVLDYVEPS-LKGTKWGLGGTCVNVGCIPKKLMHQ 92

  Fly   176 ASLLGEAVHEAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDS 240
            |:|||.||.:|..|||.:.|.:..||..:.::||||::|:||..||.|:||||:|:|..|:.:|.
Zfish    93 AALLGTAVKDARKYGWQIPETLSHDWPTMAEAVQNHVRSLNWGHRVQLQDKKVKYLNMKGTLLDK 157

  Fly   241 HTLLAKLKSG-ERTITAQTFVIAVGGRPRYP-DIPGAVEYGITSDDLFSLDREPGKTLVVGAGYI 303
            ||:.|....| |.|:||:..::|.||||:|| .:|||:|:||||||:|.|...|.|||::||.|:
Zfish   158 HTVRAVNAQGKEMTVTARNILLATGGRPKYPTHVPGAMEFGITSDDIFWLKESPKKTLIIGASYV 222

  Fly   304 GLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEKQDDGKLLV 368
            .|||||||.|:|.:.:||||||.||||||||:.||...||..|..|..|..|.||||...|.|.|
Zfish   223 SLECAGFLTGIGLDTSVMVRSIALRGFDQQMSGLVTDYMETYGTKFHWKCTPKSVEKLPSGHLQV 287

  Fly   369 KYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQKD--KIPVDSQEATNVANIYAVGD 431
            .:.::.|.||.:|.:::||||:||......|||...||.:.|:  ||.|.:.|||:|.||:|:||
Zfish   288 TWMDLNTKEEHQDTFNSVLWAVGRAPETKTLNLEKVGVKINKETGKIIVAADEATSVPNIFAIGD 352

  Fly   432 IIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEI 496
            |..|:|||||.|:.||:|||.||.|.||:.|:|::|||||||||||.|||||||:|.::.|.|:|
Zfish   353 IGEGRPELTPTAIKAGKLLAHRLAGRSTELMNYENVATTVFTPLEYGCVGLSEEEAERRHGKDQI 417

  Fly   497 EVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINT 561
            ||:|.:|||.||.:.::....||:|.|..|.|||||.|||:.||.||||.||||...:.|||...
Zfish   418 EVYHAFYKPLEFTVAERDATQCYIKVVCLREGDQRVLGLHFTGPNAGEVTQGFALGFQCGLTYEH 482

  Fly   562 LINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 594
            |.||||||||.|||.|:|.||||||||.|...|
Zfish   483 LRNTVGIHPTCAEELTKLNITKRSGLDATVTGC 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr1	NP_727251.1	DAO	59..>160	CDD:477422	30/48 (63%)
		TGR	113..595	CDD:273624	277/486 (57%)
txnrd2.2	NP_001340325.1	TGR	31..517	CDD:273624	277/486 (57%)