Protein Alignment Trxr1 and Txnrd1

DIOPT Version :10

• Sequence 1: NP_727251.1
• Gene: Trxr1 / 31760
• FlyBaseID: FBgn0020653
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001338913.1
• Gene: Txnrd1 / 58819
• RGDID: 61959
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 286/546 - (52%)
• Similarity: 361/546 - (66%)
• Gaps: 25/546 - (4%)

  Fly    62 QRG-SRDSTGATGGNAPAGSGAGAPPPFQHPHCDRAAMYAQPVRKMSTKGG------SYDYDLIV 119
            :|| .|...|...|.|..|.|....|       ::..:    :||:||...      |||:|||:
  Rat    45 RRGRGRRRAGRRRGRAEGGHGPALKP-------NKKGL----LRKLSTMNDSKDAPKSYDFDLII 98

  Fly   120 IGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVH 184
            |||||.|||.||||.....:|..||||.||| |||:||:||||||||||||||||||:|||:|:.
  Rat    99 IGGGSGGLAAAKEAAKFDKKVMVLDFVTPTP-LGTRWGLGGTCVNVGCIPKKLMHQAALLGQALK 162

  Fly   185 EAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLKS 249
            ::..|||.:::.:|.||.|:.:||||||.|:||..||.||:|||.|.|..|.|:..|.::|....
  Rat   163 DSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKVVYENAYGKFIGPHKIMATNNK 227

  Fly   250 G-ERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKG 313
            | |:..:|:.|:||.|.||||..|||..||.|:|||||||...|||||||||.|:.|||||||.|
  Rat   228 GKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAG 292

  Fly   314 LGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEKQD---DGKLLVKYKNVET 375
            :|.:.|||||||:||||||.||..:...|||.||.|:|:.||..:|:.:   .|:|.|..|:..:
  Rat   293 IGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLKVTAKSTNS 357

  Fly   376 GEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK--DKIPVDSQEATNVANIYAVGDIIYGKPE 438
            .|..||.::|||.|:||......:.|...||.:.:  .||||..:|.|||..|||:|||:.||.|
  Rat   358 EETIEDEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLE 422

  Fly   439 LTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYY 503
            |||||:.||||||:|||||||.:.||.:|.|||||||||.|.|||||.||::||.:.|||:|.::
  Rat   423 LTPVAIQAGRLLAQRLYGGSTVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFF 487

  Fly   504 KPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGI 568
            .|.|:.:|.:....||.|.|.....::||.|.|.:||.||||.||||||||.|||...|.:|:||
  Rat   488 WPLEWTVPSRDNNKCYAKVVCNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGI 552

  Fly   569 HPTTAEEFTRLAITKRSGLDPTPASC 594
            ||..||.||.|::|||||.|...:.|
  Rat   553 HPVCAEIFTTLSVTKRSGGDILQSGC 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr1	NP_727251.1	DAO	59..>160	CDD:477422	44/104 (42%)
		TGR	113..595	CDD:273624	272/488 (56%)
Txnrd1	NP_001338913.1	TGR	92..580	CDD:273624	272/488 (56%)