Protein Alignment Trxr1 and Txnrd2

DIOPT Version :10

• Sequence 1: NP_727251.1
• Gene: Trxr1 / 31760
• FlyBaseID: FBgn0020653
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_072106.1
• Gene: Txnrd2 / 50551
• RGDID: 61960
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 276/544 - (50%)
• Similarity: 360/544 - (66%)
• Gaps: 41/544 - (7%)

  Fly    55 RTMNLTGQRGSRDSTGATGGNAPAGSGAGAPPPFQHPHCDRAAMYAQPVRKMSTKGGSYDYDLIV 119
            :|..||  ||:|.:.||.                                  |..||..::||:|
  Rat    18 QTRVLT--RGTRGAAGAA----------------------------------SAAGGQQNFDLLV 46

  Fly   120 IGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVH 184
            |||||.||||||||...|.:||..|:|:|:|. |||||:||||||||||||||||||:|||..:.
  Rat    47 IGGGSGGLACAKEAAQLGRKVAVADYVEPSPR-GTKWGLGGTCVNVGCIPKKLMHQAALLGGMIR 110

  Fly   185 EAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLKS 249
            :|..|||.|.:.::.:|..:.::||||:||:||..||.|:|:||:|.|...|||:.||:....|:
  Rat   111 DAQHYGWEVAQPVQHNWKAMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVNEHTVHGVDKA 175

  Fly   250 GERT-ITAQTFVIAVGGRPRYP-DIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLK 312
            |:.| ::|:..|||.||||:|| .:.||:|:||||||:|.|...|||||||||.|:.|||||||.
  Rat   176 GKVTQLSAKHIVIATGGRPKYPTQVKGALEHGITSDDIFWLKESPGKTLVVGASYVALECAGFLT 240

  Fly   313 GLGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGE 377
            |:|.:.|||:||:.|||||||||.||...||..|..||:..||..:.|....:|.|.::::.:|:
  Rat   241 GIGLDTTVMMRSVPLRGFDQQMASLVTEHMESHGTRFLKGCVPSLIRKLPTNQLQVTWEDLASGK 305

  Fly   378 EAEDVYDTVLWAIGRKGLVDDLNLPNAGVTV--QKDKIPVDSQEATNVANIYAVGDIIYGKPELT 440
            |....:|||||||||.....:|||..|||..  :..||.||:||||:|.:|||:||:..|:||||
  Rat   306 EDVGTFDTVLWAIGRVPETRNLNLEKAGVNTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELT 370

  Fly   441 PVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKP 505
            |.|:.||:|||:||:|.|:..|:|.:|.|||||||||.|||||||:||...|.:.|||:|.||||
  Rat   371 PTAIKAGKLLAQRLFGKSSTLMNYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHIEVYHAYYKP 435

  Fly   506 TEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHP 570
            .||.:..:....||:|.|..|...|.|.|||::||.||||.||||..::.|.:...::.||||||
  Rat   436 LEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIQCGASYAQVMQTVGIHP 500

  Fly   571 TTAEEFTRLAITKRSGLDPTPASC 594
            |.:||..:|.|:||||||||...|
  Rat   501 TCSEEVVKLHISKRSGLDPTVTGC 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr1	NP_727251.1	DAO	59..>160	CDD:477422	38/100 (38%)
		TGR	113..595	CDD:273624	265/486 (55%)
Txnrd2	NP_072106.1	TGR	41..526	CDD:273624	265/485 (55%)