Protein Alignment Trxr-1 and dldh

DIOPT Version :9

• Sequence 1: NP_727251.1
• Gene: Trxr-1 / 31760
• FlyBaseID: FBgn0020653
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_958914.1
• Gene: dldh / 399479
• ZFINID: ZDB-GENE-040120-4
• Length: 507
• Species: Danio rerio
• Alignment Length: 542
• Identity: 146/542 - (26%)
• Similarity: 238/542 - (43%)
• Gaps: 69/542 - (12%)

  Fly    50 HHTFQRTMNLTGQRGSRDSTGATGGNAPAGSGAGAPPPFQHPHCDRAAMYAQPVRKMSTKGGSYD 114
            :|.: ||:...||.......|||..:|             ..:.|:||:               |
Zfish     5 NHLY-RTLATRGQHLPCKLHGATVLSA-------------RTYADKAAI---------------D 40

  Fly   115 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLL 179
            .|:.|:|.|..|...|.:|...|.:..|   |:...||      ||||:||||||.|.:...|.|
Zfish    41 ADVTVVGSGPGGYVAAIKAAQLGFKTVC---VEKNATL------GGTCLNVGCIPSKALLNNSYL 96

  Fly   180 GEAVH--EAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHT 242
            ....|  :..:.|..: :.|..:..|::......:|::........:..||.::||.|:....:.
Zfish    97 YHMAHGKDFESRGIEI-QGISLNLEKMMAQKSGAVKALTGGIAHLFKQNKVTHVNGFGTITGKNQ 160

  Fly   243 LLAKLKSGERTITAQTFVIAVGGR-PRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLE 306
            :.||...||:.|..:..:||.|.. ..:|.|....:..::|....||...|.:.:|:|||.||:|
Zfish   161 VTAKTADGEQVINTKNILIATGSEVTPFPGIEIDEDSVVSSTGALSLKNVPEELIVIGAGVIGVE 225

  Fly   307 CAGFLKGLGYEPTVM--VRSIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEKQDDGKLLVK 369
            .....:.||.:.|.:  :..:...|.|.::::.....::::|:.|...|..:...|:.|||:.|.
Zfish   226 LGSVWQRLGAKVTAVEFLGHVGGMGIDMEISKNFQRILQKQGLKFKLSTKVMGATKRPDGKIDVA 290

  Fly   370 YKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK-DKIPVDSQEATNVANIYAVGDII 433
            .:....|:......|.:|..|||:....:|.|.:.|:.:.| .:|||:.:..|||.||||:||::
Zfish   291 VEAAAGGKNETLTCDVLLVCIGRRPFTGNLGLESVGIELDKRGRIPVNGRFQTNVPNIYAIGDVV 355

  Fly   434 YGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEV 498
            .| |.|...|...|.:....:.||:. .:||..|.:.::|..|.|.||.:||. :|:.|..
Zfish   356 AG-PMLAHKAEDEGIICVEGMAGGAV-HIDYNCVPSVIYTHPEVAWVGKTEEQ-LKEEGVP---- 413

  Fly   499 FHGYYKPTEFFIPQKSVRYCYLKAVAERHG---------DQRVYGLHYIGPVAGEVIQGFAAALK 554
                ||..:|.....|    ..|..|:..|         ..|:.|.|.:|..|||:|...|.|::
Zfish   414 ----YKVGKFPFAANS----RAKTNADTDGLVKILSHKDTDRMLGAHILGSGAGEMINEAALAME 470

  Fly   555 SGLTINTLINTVGIHPTTAEEF 576
            .|.:...:......|||.:|.|
Zfish   471 YGASCEDVARVCHAHPTVSEAF 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr-1	NP_727251.1	TGR	113..595	CDD:273624	134/479 (28%)
		NADB_Rossmann	115..>150	CDD:304358	10/34 (29%)
		Pyr_redox	294..368	CDD:278498	19/75 (25%)
		Pyr_redox_dim	468..577	CDD:280934	32/118 (27%)
dldh	NP_958914.1	PRK06327	42..507	CDD:235779	133/476 (28%)
		NADB_Rossmann	44..220	CDD:304358	50/185 (27%)
		Pyr_redox	214..286	CDD:278498	17/71 (24%)
		Glycosyltransferase_GTB_type	<282..376	CDD:299143	31/94 (33%)
		Pyr_redox_dim	388..494	CDD:280934	32/118 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1249
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D581771at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820