Protein Alignment Trxr1 and Dld

DIOPT Version :10

• Sequence 1: NP_727251.1
• Gene: Trxr1 / 31760
• FlyBaseID: FBgn0020653
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_031887.2
• Gene: Dld / 13382
• MGIID: 107450
• Length: 509
• Species: Mus musculus
• Alignment Length: 498
• Identity: 136/498 - (27%)
• Similarity: 223/498 - (44%)
• Gaps: 58/498 - (11%)

  Fly    99 YA-QPVRKMSTKGGSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTC 162
            || ||:          :.|:.|||.|..|...|.::...|.:..|   ::...||      ||||
Mouse    35 YADQPI----------EADVTVIGSGPGGYVAAIKSAQLGFKTVC---IEKNETL------GGTC 80

  Fly   163 VNVGCIPKKLMHQASLLGEAVH--EAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRD 225
            :||||||.|.:...|......|  :.|:.|..:.| ::.:..|:::...:.:|::........:.
Mouse    81 LNVGCIPSKALLNNSHYYHMAHGKDFASRGIEIPE-VRLNLEKMMEQKHSAVKALTGGIAHLFKQ 144

  Fly   226 KKVEYINGLGSFVDSHTLLA-KLKSGERTITAQTFVIAVGGR-PRYPDIPGAVEYGITSDDLFSL 288
            .||.::||.|.....:.:.| |.....:.|..:..::|.|.. ..:|.|....:..::|....||
Mouse   145 NKVVHVNGFGKITGKNQVTATKADGSTQVIDTKNILVATGSEVTPFPGITIDEDTIVSSTGALSL 209

  Fly   289 DREPGKTLVVGAGYIGLECAGFLKGLGYEPTVM-----VRSIVLRGFDQQMAELVAASMEERGIP 348
            .:.|.|.:|:|||.||:|.....:.||.:.|.:     |..|   |.|.::::.....::.:|..
Mouse   210 KKVPEKLVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGI---GIDMEISKNFQRILQRQGFK 271

  Fly   349 FLRKTVPLSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQ-KDK 412
            |...|......|:.|||:.|..:....|:......|.:|..|||:....:|.|...|:.:. |.:
Mouse   272 FKLNTKVTGATKKSDGKIDVSVEAASGGKAEVITCDVLLVCIGRRPFTQNLGLEELGIELDPKGR 336

  Fly   413 IPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEY 477
            |||:::..|.:.||||:||::.| |.|...|...|.:....:.||:. .:||..|.:.::|..|.
Mouse   337 IPVNNRFQTKIPNIYAIGDVVAG-PMLAHKAEDEGIICVEGMAGGAV-HIDYNCVPSVIYTHPEV 399

  Fly   478 ACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHG---------DQRVY 533
            |.||.|||. :|:.|.:        :|..:|.....|    ..|..|:..|         ..||.
Mouse   400 AWVGKSEEQ-LKEEGIE--------FKIGKFPFAANS----RAKTNADTDGMVKILGHKSTDRVL 451

  Fly   534 GLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEF 576
            |.|.:||.|||::...|.||:.|.:...:......|||.:|.|
Mouse   452 GAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAF 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr1	NP_727251.1	DAO	59..>160	CDD:477422	15/61 (25%)
		TGR	113..595	CDD:273624	132/483 (27%)
Dld	NP_031887.2	Lpd	43..505	CDD:440861	132/480 (28%)