Protein Alignment Trxr1 and txnrd1

DIOPT Version :10

• Sequence 1: NP_727251.1
• Gene: Trxr1 / 31760
• FlyBaseID: FBgn0020653
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001243400.1
• Gene: txnrd1 / 100495372
• XenbaseID: XB-GENE-956002
• Length: 653
• Species: Xenopus tropicalis
• Alignment Length: 488
• Identity: 261/488 - (53%)
• Similarity: 330/488 - (67%)
• Gaps: 8/488 - (1%)

  Fly   113 YDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQAS 177
            ||||||||||||.|||.:|||...|.:|..||||.||| ||||||:||||||||||||||||||:
 Frog   166 YDYDLIVIGGGSGGLAASKEAANYGKKVLVLDFVTPTP-LGTKWGLGGTCVNVGCIPKKLMHQAA 229

  Fly   178 LLGEAVHEAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHT 242
            ||.:|:.::..|||.:::.|:.:|..:..||.|:|.|:|:..||.|....|:|.||.|.||:.||
 Frog   230 LLRQALKDSQKYGWQIEDNIQHNWEIMTDSVLNYIGSLNFNYRVSLMQNNVKYENGYGEFVEPHT 294

  Fly   243 LLAKLKSG-ERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLE 306
            :.:....| |:..||:.|:||.|.||||..|||..||.|||||||||...|||||||||.|:.||
 Frog   295 IKSTNSRGKEKYFTAEKFLIATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALE 359

  Fly   307 CAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIPFLRKTVPLSVEKQD---DGKLLV 368
            |||||.|||.:.|||||||:|||||||||.::...|||.|:.|:::.||..:|:.:   .|:|.|
 Frog   360 CAGFLAGLGLDVTVMVRSILLRGFDQQMANMIGEYMEEHGVKFIKQCVPTKIEQIEAGTPGRLKV 424

  Fly   369 KYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQK--DKIPVDSQEATNVANIYAVGD 431
            . .....|.|..:.|:|||.||||.....::.|...||.:.:  .||||:.:|.|||..|||:||
 Frog   425 T-SQASDGAETTEEYNTVLLAIGRDACTRNIGLEIPGVKINEKTGKIPVNDEEQTNVPYIYAIGD 488

  Fly   432 IIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEI 496
            ::..|.||||||:.|||||||||||.||.:.||.:|.|||||||||...|||||.|::|:..:.|
 Frog   489 VLQDKLELTPVAIQAGRLLARRLYGDSTVKCDYVNVPTTVFTPLEYGACGLSEEHAIRQYEEENI 553

  Fly   497 EVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINT 561
            ||:|.|:.|.|:.:|.:....||.|.:.......||.|.|.:.|.|||:.||||.|:|.|||.:.
 Frog   554 EVYHSYFWPLEWTVPARDNNKCYAKIICNLKDKGRVVGFHVLSPNAGEITQGFAVAIKCGLTKDQ 618

  Fly   562 LINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 594
            |.||:||||..||.||.|.:|||||.:...:.|
 Frog   619 LDNTIGIHPVCAEIFTTLTVTKRSGGNILQSGC 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr1	NP_727251.1	DAO	59..>160	CDD:477422	33/46 (72%)
		TGR	113..595	CDD:273624	261/488 (53%)
txnrd1	NP_001243400.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	73..153	CDD:469754
		TGR	166..653	CDD:273624	261/488 (53%)