DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10761 and MARCHF1

DIOPT Version :9

Sequence 1:NP_572456.1 Gene:CG10761 / 31749 FlyBaseID:FBgn0030015 Length:323 Species:Drosophila melanogaster
Sequence 2:NP_001381888.1 Gene:MARCHF1 / 55016 HGNCID:26077 Length:545 Species:Homo sapiens


Alignment Length:248 Identity:55/248 - (22%)
Similarity:99/248 - (39%) Gaps:70/248 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 EPPSGNVVDD-----RMCWIC-LRGDEDHRRRDWVHPCRCRGTNKWVHEACLSRWIDEKEMLSPG 80
            :||:  ..||     .:|.|| ..|||:   ...:.||||.||.::||::||.:||...:..   
Human   321 KPPA--TYDDGSDNLEVCRICHCEGDEE---SPLITPCRCTGTLRFVHQSCLHQWIKSSDTR--- 377

  Fly    81 APVTCTQCRTEYII--VMPPLCRFDAMLERLDKGCDRMCPSVLMGILAAT-VYFSAVIY------ 136
               .|..|:.::|:  .:.||.:::.:.....:.....| ||...::|.| |.:|..:.      
Human   378 ---CCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIFC-SVTFHVIAITCVVWSLYVLIDRTAE 438

  Fly   137 --------GAL-------TVLQLAGYSTGMKLLQEDPSLLMIVLPSV-----PTLLLLSRLVRWE 181
                    |.|       .|:...|::.|:        :.|.|...|     ..|...:|::..:
Human   439 EIKQGNDNGVLEWPFWTKLVVVAIGFTGGL--------VFMYVQCKVYVQLWRRLKAYNRVIFVQ 495

  Fly   182 DC--VIRWLRRRKRSAIPAEQLDAVGLPLP--GAPLSDEYFDELEREYPASDG 230
            :|  ..:.|.:.....:..:..|||.:|:|  ||           ...|:::|
Human   496 NCPDTAKKLEKNFSCNVNTDIKDAVVVPVPQTGA-----------NSLPSAEG 537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10761NP_572456.1 RINGv 33..89 CDD:128983 19/56 (34%)
MARCHF1NP_001381888.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R328
SonicParanoid 1 1.000 - - X270
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.940

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