Protein Alignment CG10761 and MARCHF5

DIOPT Version :9

• Sequence 1: NP_572456.1
• Gene: CG10761 / 31749
• FlyBaseID: FBgn0030015
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_060294.1
• Gene: MARCHF5 / 54708
• HGNCID: 26025
• Length: 278
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 104/284 - (36%)
• Similarity: 161/284 - (56%)
• Gaps: 24/284 - (8%)

  Fly    31 DRMCWICLRGDEDHRRRDWVHPCRCRGTNKWVHEACLSRWIDEKEMLSPGAPVTCTQCRTEYIIV 95
            ||.||:|...|||.|..:||.||||||:.||||:|||.||:|||:..:..|.|.|.||..||:||
Human    11 DRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIV 75

  Fly    96 MPPLCRFDAMLERLDKGCDRMCPSVLMGILAATVYFSAVIYGALTVLQLAGYSTGMKLLQE-DPS 159
            .|.|.....:|:..|:...:.||....||:..::|::||.|||:||:|:.|:..|:.:::. ||.
Human    76 FPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPL 140

  Fly   160 LLMIVLPSVPTLLLLSRLVRWEDCVIR-WLRRRKRSAIPAEQLDAVGLPLPGAPLSDEYFDELER 223
            .|:|.||::|.:|:|.:::||||.|:| |.:...:..|.......:|.|:|..|....
Human   141 FLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEAN------- 198

  Fly   224 EYPASDGLIGGNLATEQLGRASTSFCIALSLPTISVVLGQKLFGRIYEENKLLSILLGGLTFVTI 288
              |.:|.:           .|:...|.||..|||:.::|:.:|..:  .:.|...:|||:.||.|
Human   199 --PLADHV-----------SATRILCGALVFPTIATIVGKLMFSSV--NSNLQRTILGGIAFVAI 248

  Fly   289 KGLASIFLSQSQYQQRRHRFVMDY 312
            ||...::..|.||.::.||.:::|
Human   249 KGAFKVYFKQQQYLRQAHRKILNY 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10761	NP_572456.1	RINGv	33..89	CDD:128983	31/55 (56%)
MARCHF5	NP_060294.1	RING_CH-C4HC3_MARCH5	12..72	CDD:319615	33/59 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153122
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6573
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1210654at2759
OrthoFinder	1	1.000	-	-		FOG0003968
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X270
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.760