DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10761 and CG9855

DIOPT Version :9

Sequence 1:	NP_572456.1	Gene:	CG10761 / 31749	FlyBaseID:	FBgn0030015	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001262253.1	Gene:	CG9855 / 40556	FlyBaseID:	FBgn0037242	Length:	382	Species:	Drosophila melanogaster

Alignment Length:	309	Identity:	129/309 - (41%)
Similarity:	177/309 - (57%)	Gaps:	30/309 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GLEPPSGNVVDDRMCWICLRGDEDHRRRDWVHPCRCRGTNKWVHEACLSRWIDEKEMLSPG-APV 83
            |.||       :|.||||...|||:|...||.||:||||.||||::||.||||||...... ..|
  Fly    58 GGEP-------ERCCWICFATDEDNRLAAWVKPCQCRGTTKWVHQSCLYRWIDEKTQKGNALRTV 115

  Fly    84 TCTQCRTEYIIVMPPLCRFDAMLERLDKGCDRMCPSVLMGILAATVYFSAVIYGALTVLQLAGYS 148
            :|.||:||||||.|.:.:....||.:|....|:.|.:..|....::|::||.|||:|.||:.|:.
  Fly   116 SCPQCQTEYIIVFPQMGKLGGALEAIDNLIKRLSPFLAAGFFVGSLYWTAVTYGAVTFLQIVGHE 180

  Fly   149 TGMKLLQE-DPSLLMIVLPSVPTLLLLSRLVRWEDCVIRWLRRRKRSAIPAEQLDAVGLPLPGAP 212
            .||.:::. ||.:|:|.||::|..|:|.||:||||.::|.:|.|   .....:...|.|..|.
  Fly   181 HGMSIMESGDPLVLLIGLPAIPVGLVLGRLIRWEDALLRLIRNR---GTVVRKFPFVSLIYPN-- 240

  Fly   213 LSDEYFDELEREYPASDGLIGGNLATEQLG---RASTSFCIALSLPTISVVLGQKLFGRIYEENK 274
            ||.|     |.:...|      |.||..|.   .|:..||.||.|||||.::|:.||..:  :|.
  Fly   241 LSQE-----EEQQSIS------NPATPALSDPVSATRVFCGALLLPTISSIVGRILFDTV--DNT 292

  Fly   275 LLSILLGGLTFVTIKGLASIFLSQSQYQQRRHRFVMDYTPRNRINYQSR 323
            |...|||||||:|:||:..|:|.|.||.:|:.|.::|||..|..|:..|
  Fly   293 LHRTLLGGLTFITVKGILKIYLKQKQYGRRKKRRIVDYTEENIRNFMHR 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10761	NP_572456.1	RINGv	33..89	CDD:128983	31/56 (55%)
CG9855	NP_001262253.1	RINGv	64..121	CDD:128983	31/56 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458030
Domainoid	1	1.000	47	1.000	Domainoid score	I4521
eggNOG	1	0.900	-	-		E1_KOG3053
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6573
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1210654at2759
OrthoFinder	1	1.000	-	-		FOG0003968
OrthoInspector	1	1.000	-	-		otm14746
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X270
	10	9.800