DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GIIIspla2 and OC90

DIOPT Version :9

Sequence 1:	NP_001285008.1	Gene:	GIIIspla2 / 31747	FlyBaseID:	FBgn0030013	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001073868.2	Gene:	OC90 / 729330	HGNCID:	8100	Length:	477	Species:	Homo sapiens

Alignment Length:	176	Identity:	37/176 - (21%)
Similarity:	56/176 - (31%)	Gaps:	61/176 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 QLSDWLIAPNTR----------WC---GRGNLANGTYNDLGGASKADKCCRKHDHCKMWIDGMSN 130
            ||.:.|....:|          :|   |||.    ..:||      |:||..|..|...:..:..
Human   307 QLGEMLFCLTSRCPEEFESYGCYCGQEGRGE----PRDDL------DRCCLSHHCCLEQVRRLGC 361

  Fly   131 RYDLFNYRPYT-LSH--------------CSCDLRFRTCLKMAG-DEDANAIGKLFFNVVQTQCF 179
            ..:...:.|.. :.|              |:||.....|:..|. ::...:..:|       .|.
Human   362 LLERLPWSPVVCVDHTPKCGGQSLCEKLLCACDQTAAECMTSASFNQSLKSPSRL-------GCP 419

  Fly   180 GLKAETVCVQR----------GGSGK---ETDPCLKEEVRHKAFLR 212
            |..|  .|...          |.|.:   |.||..::..|.|.|||
Human   420 GQPA--ACEDSLHPVPAAPTLGSSSEEDSEEDPPQEDLGRAKRFLR 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GIIIspla2	NP_001285008.1	PLA2_bee_venom_like	84..181	CDD:153093	22/125 (18%)
OC90	NP_001073868.2	Phospholipase A2-like 1	76..190
		otoconin_90	78..195	CDD:153096
		Phospholipase A2-like 2	305..361		15/63 (24%)
		otoconin_90	307..423	CDD:153096	25/132 (19%)
		Phospholipase A2-like 3	373..425		10/60 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	428..477		10/36 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1422829at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010