DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GIIIspla2 and Pla2g3

DIOPT Version :9

Sequence 1:	NP_001285008.1	Gene:	GIIIspla2 / 31747	FlyBaseID:	FBgn0030013	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001099485.1	Gene:	Pla2g3 / 289733	RGDID:	1305323	Length:	506	Species:	Rattus norvegicus

Alignment Length:	193	Identity:	73/193 - (37%)
Similarity:	95/193 - (49%)	Gaps:	25/193 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IANERTICALMPL--VILATWQLCLLPGTDAKHLAIRLRDPQSEIE----SETVPLAHVHSHSHT 61
            ||..|.:||..||  ..:.|      ||.:.:.....|   ||:.|    ||..|.......
  Rat    80 IAAFRALCAHEPLRHAFIHT------PGPELQRALATL---QSQWEACRRSEASPTGAREKR--- 132

  Fly    62 DESGVRGA-AAVHRRERRQLSDWLIAPNTRWCGRGNLANGTYNDLGGASKADKCCRKHDHCKMWI 125
             |:..||| |..|:|.||   .|.| |.|.|||.||.|... ::||.....|.|||:||.|...|
  Rat   133 -ETEHRGAPAGEHQRRRR---GWTI-PGTLWCGVGNSAENA-SELGMFHGPDFCCREHDQCPQTI 191

  Fly   126 DGMSNRYDLFNYRPYTLSHCSCDLRFRTCLKMAGDEDANAIGKLFFNVVQTQCFGLKAETVCV 188
            ..:...|.:.|:|.:|:|||.||.||:.||:..||..|:.:|..||||::..||.||.:..||
  Rat   192 SPLQYNYGIRNFRFHTISHCDCDARFQQCLRSQGDSIADIMGVAFFNVLEIPCFVLKEQETCV 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GIIIspla2	NP_001285008.1	PLA2_bee_venom_like	84..181	CDD:153093	42/96 (44%)
Pla2g3	NP_001099485.1	PLA2_bee_venom_like	151..247	CDD:153093	43/97 (44%)
Pla2g3	NP_001099485.1	PLA2_group_III_like	299..424	CDD:153094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339588
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28MF1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003412
OrthoInspector	1	1.000	-	-		oto96448
orthoMCL	1	0.900	-	-		OOG6_116629
Panther	1	1.100	-	-	O	PTHR12253
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3866
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.700