DRSC/TRiP Functional Genomics Resources

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Protein Alignment GIIIspla2 and Pla2g3

DIOPT Version :9

Sequence 1:NP_001285008.1 Gene:GIIIspla2 / 31747 FlyBaseID:FBgn0030013 Length:217 Species:Drosophila melanogaster
Sequence 2:NP_766379.2 Gene:Pla2g3 / 237625 MGIID:2444945 Length:504 Species:Mus musculus


Alignment Length:211 Identity:68/211 - (32%)
Similarity:91/211 - (43%) Gaps:55/211 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 GTDAKHLAI---------RLRDPQSEIESETV----------PLAH------------------- 54
            |.||:.||:         ||:....:.|||.:          ||.|                   
Mouse    45 GKDAQGLALFQAFWDTHHRLQVCIRQDESELITAFRALCAHEPLQHSFIQTPGPALQRALATLQS 109

  Fly    55 ---VHSHSHTDESGVRGAAAV---------HRRERRQLSDWLIAPNTRWCGRGNLANGTYNDLGG 107
               ....|....:|.|...|:         |||.||   .|.| |.|.|||.||.|... ::||.
Mouse   110 QWEACQRSQDSPTGAREKRAIEQSGAPDREHRRRRR---GWTI-PGTLWCGVGNSAENA-SELGV 169

  Fly   108 ASKADKCCRKHDHCKMWIDGMSNRYDLFNYRPYTLSHCSCDLRFRTCLKMAGDEDANAIGKLFFN 172
            ....|.|||:||.|...|..:...|.:.|:|.:|:|||.||.||:.||:..||..::.:|..|||
Mouse   170 FHGPDLCCREHDQCPQTISPLQYNYGIRNFRFHTISHCDCDARFQQCLRSQGDSISDIMGVAFFN 234

  Fly   173 VVQTQCFGLKAETVCV 188
            |::..||.||.:..||
Mouse   235 VLEIPCFVLKEQEACV 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GIIIspla2NP_001285008.1 PLA2_bee_venom_like 84..181 CDD:153093 41/96 (43%)
Pla2g3NP_766379.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 115..143 6/27 (22%)
Phospholipase A2-like. /evidence=ECO:0000250|UniProtKB:Q9NZ20 146..287 46/107 (43%)
PLA2_bee_venom_like 147..243 CDD:153093 42/97 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 285..350
PLA2_group_III_like 295..422 CDD:153094
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167835950
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_28MF1
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S8069
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0003412
OrthoInspector 1 1.000 - - otm42980
orthoMCL 1 0.900 - - OOG6_116629
Panther 1 1.100 - - O PTHR12253
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5827
SonicParanoid 1 1.000 - - X3866
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1110.680

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