DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GIIIspla2 and PROCA1

DIOPT Version :9

Sequence 1:	NP_001285008.1	Gene:	GIIIspla2 / 31747	FlyBaseID:	FBgn0030013	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001353230.1	Gene:	PROCA1 / 147011	HGNCID:	28600	Length:	364	Species:	Homo sapiens

Alignment Length:	154	Identity:	36/154 - (23%)
Similarity:	65/154 - (42%)	Gaps:	37/154 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 RERRQLSDWLIAPNTRWCGRGNLANG--------TYNDLGGASKADKCCRKHDHCKMWI------ 125
            |:..:|..|         .||:|..|        |::: |...:.||||.:|..|...|
Human    30 RDVNRLPSW---------ERGHLLAGVASSTDVSTFSE-GDCKEPDKCCWRHKQCTGHIIYPFAS 84

  Fly   126 DGMSNRYDLFNYRPYTLSHCSCDLRFRTCLKMAGDEDANA--IGKLFFNVVQTQCFGLKAETVCV 188
            |.:.:...|     ::::||:|:.|    ||.:.::.:::  .|....:|:::.||.|..|...|
Human    85 DCVRHSLHL-----HSVNHCNCNSR----LKDSSEDSSSSRGAGPTCSHVIESPCFELTPEEEHV 140

  Fly   189 QRGGSG--KETDPCLKEEVRHKAF 210
            :|...|  |...|.....:.|..:
Human   141 ERFRYGWCKSYRPVSVAVIHHPLY 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GIIIspla2	NP_001285008.1	PLA2_bee_venom_like	84..181	CDD:153093	25/112 (22%)
PROCA1	NP_001353230.1	PLA2_group_III_like	33..132	CDD:153094	26/117 (22%)
PROCA1	NP_001353230.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	172..364
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145869
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28MF1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840