Protein Alignment Traf6 and Rnf41

DIOPT Version :10

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_080535.2
• Gene: Rnf41 / 67588
• MGIID: 1914838
• Length: 317
• Species: Mus musculus
• Alignment Length: 244
• Identity: 57/244 - (23%)
• Similarity: 86/244 - (35%)
• Gaps: 69/244 - (28%)

  Fly    91 GEQEEELLDSRYECAICIDWLNEPV-LTSCGHRFCRSCLTAWMQKNNQCCPMDNKRLSAEHDIFP 154
            |:.:|:|:     |.||...|.||| ...|.|.||.:|:|.|..: .|.||:|...::..|....
Mouse    10 GDVDEDLI-----CPICSGVLEEPVQAPHCEHAFCNACITQWFSQ-QQTCPVDRSVVTVAHLRPV 68

  Fly   155 DNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRRQQEPQEEKCPFAKIKCDFVGRPE 219
            ....|..:.:|:..|.|:..|||.|.....|..||..|          |..|...:.|      |
Mouse    69 PRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDC----------EHNPKRPVTC------E 117

  Fly   220 TNQLEEHLKADMPHHMQLMLQAFQQTAIATWQPHKPSTSGAAVENGHGQQQLPPPPQYANGVDEQ 284
            .....|..|.::|:|..:              .|..|
Mouse   118 QGCGLEMPKDELPNHNCI--------------KHLRS---------------------------- 140

  Fly   285 IVQTMYQRIVVLEQRTREQETRLENMQKQLRL----ARQQAPVDPRYSN 329
            :||....||..||:.:.|.:.:|...::.::|    .|....|:|...|
Mouse   141 VVQQQQSRIAELEKTSAEHKHQLAEQKRDIQLLKAYMRAIRSVNPNLQN 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	mRING-HC-C3HC3D_LNX1-like	101..143	CDD:438299	17/42 (40%)
		Sina	169..>230	CDD:460824	16/60 (27%)
		MATH_TRAF6	330..473	CDD:239745	57/244 (23%)
Rnf41	NP_080535.2	mRING-HC-C3HC3D_Nrdp1	15..57	CDD:438296	18/47 (38%)
		USP8_interact	137..315	CDD:430333	15/81 (19%)