Protein Alignment Traf6 and traf2b

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_005165556.1
• Gene: traf2b / 557526
• ZFINID: ZDB-GENE-030131-5345
• Length: 532
• Species: Danio rerio
• Alignment Length: 564
• Identity: 116/564 - (20%)
• Similarity: 189/564 - (33%)
• Gaps: 209/564 - (37%)

  Fly    69 PTPPKSLALNQNHHYAPGSDTSGEQEEEL---LDSRYECAICIDWLNEPVLTSCGHRFCRSCLTA 130
            |:.|.||          .|...|...|.|   ::.:|:|..|.|.|.:|....||||||..|.
Zfish    17 PSLPSSL----------DSTLPGISREVLSVSMEPKYQCQQCKDILRKPFQAQCGHRFCVFCF-- 69

  Fly   131 WMQKNNQCCPMDNKRLSAEHDI-----------------------FPDNYTRREIEQLKRDCPNS 172
                         |:|::...|                       ||||..||||:.|...|||.
Zfish    70 -------------KQLTSSGPIPCEACRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNE 121

  Fly   173 SL-------------------------GCSVVASPIELHRH--------LPSCPY---------- 194
            ..                         .|.|:....|..||        ..:|.|
Zfish   122 GCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCKVTFNFKEI 186

  Fly   195 -----------------RRQQEPQEE-------------KCPFAKIKCDFVGRPETNQLEEHLKA 229
                             .:::.|:|:             .|.|.:|.|..|  .:..:.:||.:.
Zfish   187 KAHDEICQKFPMQCKDCGKKKIPREKFQEHTKSCAKSKSACQFREIGCRAV--VDNCKQQEHEQT 249

  Fly   230 DMPHHMQLMLQAFQQTAI-----ATWQPHKPSTSGAAVENGHGQQQLP--PPPQYANGVD----- 282
            .:..|::|||.......:     ..||.          :.|.|..:.|  .||..|:.|.
Zfish   250 SIMEHLRLMLALLSSMRLRAEGAGEWQE----------DVGLGLYRGPEDAPPAGAHNVGRGGGP 304

  Fly   283 --EQIVQTMYQRIVVLEQRT--------------REQETRLENMQKQLR-LARQQAPVDPRYS-- 328
              ::.|.|:...:.||.:..              |..:.::||:..::| |.|.....|.:.:
Zfish   305 GVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAES 369

  Fly   329 ------------NGTIVWRIEQLG-----ALVARLRANANNQVYSHECYTSPHGYKFCARLNIQ- 375
                        :|..:|:|.:..     |:..|..|     ::|...|:|.:|||.|.||.:.
Zfish   370 EQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPA-----MFSPAFYSSKYGYKMCLRLYLNG 429

  Fly   376 ---PRKPHVLSLHVHLMQSENDYHLDWPFKGRIKLCMVHPADATLSQHDTIMTKPEI--LAFHKP 435
               .|..| |||...:|:.:.|..|.|||..::.|.::   |....:|.....:|::  .:|.:|
Zfish   430 DGTGRGSH-LSLFFVVMKGKYDALLKWPFSQKVTLMLL---DQNNREHIIDAFRPDVSSTSFQRP 490

  Fly   436 REAISTRGFG-----FLEYANISNIIQLGFCADDRLLIKIEINI 474
               ||.....     |...|.::.  :..:..||.:.||..:::
Zfish   491 ---ISEMNIASGCPLFCPLAKLAG--KSSYLRDDTIFIKAIVDL 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	12/37 (32%)
		Sina	163..>230	CDD:302762	20/139 (14%)
		MATH_TRAF6	330..473	CDD:239745	40/158 (25%)
traf2b	XP_005165556.1	RING	44..86	CDD:238093	15/56 (27%)
		zf-TRAF	189..246	CDD:280357	7/58 (12%)
		TRAF_BIRC3_bd	307..359	CDD:293278	10/51 (20%)
		MATH_TRAF2	365..528	CDD:239747	40/176 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920