Protein Alignment Traf6 and traf6

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001038217.1
• Gene: traf6 / 554561
• ZFINID: ZDB-GENE-030131-5735
• Length: 542
• Species: Danio rerio
• Alignment Length: 543
• Identity: 140/543 - (25%)
• Similarity: 217/543 - (39%)
• Gaps: 132/543 - (24%)

  Fly    20 HSHAHSLQHAEEKEHNSNEMTTNLSSTGRIAASSSATPSAAAGGGASGAPTPPKSLALNQNHHYA 84
            ||   |...|.|||..|....|...||  |:.|||..|...   |......||
Zfish    20 HS---SCAAAMEKERESFLSPTENPST--ISVSSSMPPDQQ---GYDVEFDPP------------ 64

  Fly    85 PGSDTSGEQEEELLDSRYECAICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCPMDNKRLSAE 149
                         |:|:|||.||:..|...|.|.||||||.||:...::...|.||:||:.| .|
Zfish    65 -------------LESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCPVDNEVL-LE 115

  Fly   150 HDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRRQQEPQ------------- 201
            ..:||||:.:|||..|...|  |:.|||......:|.:||..|.:.....||
Zfish   116 EQLFPDNFAKREILSLTVKC--SNFGCSEKMELRQLEKHLSQCRFATAPCPQCQESVPISHLDEH 178

  Fly   202 ---------------------------EEKCPFAKIKCDFV------------------------ 215
                                       |:.||||...|::.
Zfish   179 KSQHCLQRIMTCPDCAGSFVYAVKQNHEQFCPFANTVCEYCEMELIRDQLALHCDTDCLKAPVAC 243

  Fly   216 --------GRPETNQLEEHLKADMPHHMQLMLQAFQQTAIATWQPHKPSTSGAAVENGHGQQQLP 272
                    .:...|:|.:|::.....||:.|.:..:...:....  .||.:.....:..|.....
Zfish   244 TFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCT--MPSAAAHLSSDDRGASARS 306

  Fly   273 PP----PQYANGVDEQIVQTMYQRIVVLEQRTRE-------QETRLENMQKQL-RLARQQAPVDP 325
            |.    .|....:.|.::: :..|:|..:|:.||       |:.::..::::| .|......::.
Zfish   307 PDSCQCKQELLNLRETVLE-LEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEA 370

  Fly   326 RYSNGTIVWRIEQLGALVARLRANANNQVYSHECYTSPHGYKFCARLNIQ----PRKPHVLSLHV 386
            :...|..|||:|.....:....|.....::|...||...|||.|.||::|    ||..:.:||.|
Zfish   371 QQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFV 435

  Fly   387 HLMQSENDYHLDWPFKGRIKLCMVHPADATLSQH--DTIMTKPEILAFHKPREAISTRGFGFLEY 449
            |.||.|.|..|.||.:|.|:|.::   |....||  :.:.|||::.||.:|....:.:|||::.:
Zfish   436 HTMQGEFDSQLSWPLQGTIRLAVL---DQVEGQHHIEVMETKPDLQAFQRPTVMRNPKGFGYVTF 497

  Fly   450 ANISNIIQLGFCADDRLLIKIEI 472
            .::..:.|.||..:|.||::.|:
Zfish   498 LHLQALRQRGFVKEDVLLVRCEV 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	17/37 (46%)
		Sina	163..>230	CDD:302762	21/138 (15%)
		MATH_TRAF6	330..473	CDD:239745	51/149 (34%)
traf6	NP_001038217.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..54		9/23 (39%)
		RING	71..108	CDD:214546	16/36 (44%)
		zf-TRAF	205..262	CDD:280357	8/56 (14%)
		MATH_TRAF6	375..521	CDD:239745	51/149 (34%)
		Substrate binding. /evidence=ECO:0000250	489..496		3/6 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583658
Domainoid	1	1.000	96	1.000	Domainoid score	I7305
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3395
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4233
OMA	1	1.010	-	-		QHG50043
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	1	1.000	-	-		FOG0008003
OrthoInspector	1	1.000	-	-		oto41535
orthoMCL	1	0.900	-	-		OOG6_109516
Panther	1	1.100	-	-	LDO	PTHR10131
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5828
SonicParanoid	1	1.000	-	-		X5961
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800