Protein Alignment Traf6 and traf3

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001003513.1
• Gene: traf3 / 445119
• ZFINID: ZDB-GENE-040801-257
• Length: 573
• Species: Danio rerio
• Alignment Length: 562
• Identity: 118/562 - (20%)
• Similarity: 184/562 - (32%)
• Gaps: 172/562 - (30%)

  Fly    72 PKSLA---LNQNHHYAPG-SDTSGEQEEELL---DSRYECAICIDWLNEPVLTSCGHRFCRSCLT 129
            |.|||   :.|.....|| |...|...:..:   :.:|.|..|...|..|..|.||||||.||:.
Zfish    17 PPSLAMPSMAQRPRPEPGFSPLHGGFRDHFVTTPEPKYCCETCRLVLCNPRQTECGHRFCESCIN 81

  Fly   130 AWMQKNNQCCPMDNKRLSAEHDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPY 194
            ..:.|.|..||.|...| .|..||.|....|||..||..|.:...||.......::..||..|||
Zfish    82 ELLSKPNPVCPADLLPL-FEDKIFRDVCCNREIMALKVYCRSEKNGCKEQMCLQQVMEHLVICPY 145

  Fly   195 ----------------------------------------------------------------- 194
                                                                             
Zfish   146 FEVPCPLGKCKEKMMRKDMPEHLSRKCKHREVTCEFCSLKMALTELQKHKETVCPAFPVACPNHC 210

  Fly   195 ------RRQQEPQEEKCPFAKIKCDFVG-----RPETNQLEEHLKADMPHHMQLMLQAFQQTAIA 248
                  |.:....:..||.|::.|.|:.     :....::.||..:....|:::|  |.:.|.:.
Zfish   211 SFSSILRSELSSHQHDCPKAQVTCSFIRYGCSYKGLNQEMREHESSFASEHLRMM--AVRNTTLE 273

  Fly   249 T---------WQPHK--PSTSGAAVE-----------NGHGQQQLPPPPQYANGVDEQI--VQTM 289
            .         .:.:|  ||.|....|           |...:|:|.......:...|::  |:..
Zfish   274 AKVEDVKSELMERYKVLPSLSSRLAEVERQYEEMREKNRQLEQKLVSMQMLMSSHSEKLLEVEME 338

  Fly   290 YQRIVVLEQRTREQET---------------------------RLENMQKQL------------R 315
            .:.:..|.....|.||                           .|.::::||            |
Zfish   339 LRELRPLRAMREEVETLRGSVESMRSMVSSLDSSCVNSASGSHTLASLEQQLTRHDDLMSVHDVR 403

  Fly   316 LARQQAP---VDPRYSNGTIVWRIEQLGALVARLRANANNQVYSHECYTSPHGYKFCARLNI--- 374
            ||.....   ::....|||::|:|............:....:||...||...|||.|||:.:
Zfish   404 LAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGD 468

  Fly   375 -QPRKPHVLSLHVHLMQSENDYHLDWPFKGRIKLCMVHPADATLSQHDTIMTKPEILAFHKPREA 438
             ..:..| |||...:|:.|.|..|.||||.::.|.::....|.....|.....|...:|.:|.
Zfish   469 GMGKGTH-LSLFFVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPDPSSSSFRRPT-- 530

  Fly   439 ISTRGFGFLEYAN------ISNIIQLG-FCADDRLLIKIEIN 473
                  |.:..|:      ...:::.| :..||.:.||:.::
Zfish   531 ------GEMNIASGCPLFVAQTVLENGTYIKDDTIFIKVTVD 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	16/37 (43%)
		Sina	163..>230	CDD:302762	18/142 (13%)
		MATH_TRAF6	330..473	CDD:239745	39/153 (25%)
traf3	NP_001003513.1	RING	55..92	CDD:214546	15/36 (42%)
		zf-TRAF	139..194	CDD:280357	5/54 (9%)
		zf-TRAF	198..253	CDD:280357	6/54 (11%)
		Prefoldin	<249..322	CDD:298833	14/74 (19%)
		MATH_TRAF3	383..568	CDD:239746	46/193 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4233
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.970