DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Traf6 and Lnx1

DIOPT Version :9

Sequence 1:	NP_511080.2	Gene:	Traf6 / 31746	FlyBaseID:	FBgn0265464	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001101828.1	Gene:	Lnx1 / 360926	RGDID:	1308159	Length:	728	Species:	Rattus norvegicus

Alignment Length:	155	Identity:	42/155 - (27%)
Similarity:	65/155 - (41%)	Gaps:	28/155 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 PTP-PKSLALNQNHHYAPGSDTSGEQEE-----ELLDSRYECAICIDWLNEPVLTSCGHRFCRSC 127
            |:| |..:...|||        |.|:..     |.:|....|.||:..|.:|:.|.|||.:|..|
  Rat    12 PSPEPLCVVCGQNH--------SPEENHFYTYTEDVDDDLVCHICLQALLDPLDTPCGHTYCTLC 68

  Fly   128 LTAWMQKNNQCCPMDNKRLSAEHDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHL-PS 191
            ||.::.:.: .||:|.|.:..:|....:....:.:.:|..:||.:. .||.|.....|..|. .|
  Rat    69 LTNFLVEKD-FCPVDRKPVVLQHCKKSNILVNKLLNKLLVNCPFTE-HCSEVLQRCNLQYHFQTS 131

  Fly   192 CP-----------YRRQQEPQEEKC 205
            |.           .||.|:...:.|
  Rat   132 CKGASHYGLTKDRKRRSQDGCPDGC 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	14/37 (38%)
		Sina	163..>230	CDD:302762	14/55 (25%)
		MATH_TRAF6	330..473	CDD:239745
Lnx1	NP_001101828.1	RING	45..81	CDD:214546	14/36 (39%)
		DegQ	<260..364	CDD:223343
		PDZ_signaling	276..360	CDD:238492
		PDZ_signaling	384..464	CDD:238492
		PDZ_signaling	506..589	CDD:238492
		PDZ_signaling	637..721	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810