DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Traf6 and CG9014

DIOPT Version :9

Sequence 1:	NP_511080.2	Gene:	Traf6 / 31746	FlyBaseID:	FBgn0265464	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001285905.1	Gene:	CG9014 / 34777	FlyBaseID:	FBgn0028847	Length:	328	Species:	Drosophila melanogaster

Alignment Length:	154	Identity:	47/154 - (30%)
Similarity:	71/154 - (46%)	Gaps:	27/154 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 GEQEEELLDSRYECAICIDWLNEPVLTS-CGHRFCRSCLTAWM-QKNNQCCPMDNKRLSAEHDIF 153
            |..:|||:     |.||.|.|.|||.:| |.|.|||:|:..|| ||  |.||:|...|...|.:.
  Fly    10 GHVDEELI-----CPICTDVLEEPVQSSECEHAFCRACIDKWMIQK--QICPVDRSGLLTSHLVP 67

  Fly   154 PDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRRQ-----------QEPQEEKCPF 207
            .....|..:.:||..|..|..||:.:.:..|...|:.:|.:..:           :.|::|   .
  Fly    68 VSRLMRNMLSRLKIKCTFSQSGCAQMLALEEFRTHVAACEHNPKVVVECSKGCGMKVPKDE---M 129

  Fly   208 AKIKCDFVGRPETNQLEEHLKADM 231
            ::..|.|    |..:|.|.|..::
  Fly   130 SRHNCVF----ELRELVEKLAKEV 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	21/39 (54%)
		Sina	163..>230	CDD:302762	17/77 (22%)
		MATH_TRAF6	330..473	CDD:239745
CG9014	NP_001285905.1	zf-C3HC4	18..55	CDD:278524	21/38 (55%)
CG9014	NP_001285905.1	USP8_interact	137..319	CDD:286082	4/13 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.820