Protein Alignment Traf6 and Traf-like

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_727976.1
• Gene: Traf-like / 32611
• FlyBaseID: FBgn0030748
• Length: 474
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 84/476 - (17%)
• Similarity: 154/476 - (32%)
• Gaps: 144/476 - (30%)

  Fly    78 NQNHHY-APGSDTSGEQEEELLDSRYECAICIDWLNEPVLTS----CGH--RFCRSCLTAW---- 131
            |||.:. .|.|.|..:.|:.      .|..|.:|.:....|.    ||.  ..|.:...|:
  Fly    20 NQNENQNQPKSTTIVKYEKS------SCLFCNEWFDAQTFTEHLIHCGQVLEECPNGCQAFIPRI 78

  Fly   132 -MQKNNQCCPMDNKRLSAEH--DIFPDNYTRREIEQL---KRDCPNSSLGC--SVVASPIELHRH 188
             |:.:.:.||.:...||.:.  .:..|...|:..::|   ::|     :|.  ||:...|....|
  Fly    79 RMRSHLKECPRNQHNLSNQQRMSVSMDRLDRQSDQRLLVIEQD-----VGTIRSVLNEEIRQRLH 138

  Fly   189 L-----------------------PSCPYRRQQEPQEEKCPFA--------KIKCDFVGR----- 217
            |                       .....|||.|.:..:..||        :..||....
  Fly   139 LITDVGNIRKQNQVVEDWTRETEKAMDDLRRQMEEETNRKAFAIEQNQLDVQYCCDITQSLKEQV 203

  Fly   218 ----PETNQLEEHLKADMPHHMQ------------------------LMLQAFQQ-------TAI 247
                .|..:|...|.||:.:|..                        ..::.|.|       |.:
  Fly   204 ESRLDEAQKLVNQLSADVTYHQNQLNDNILKLEELIFENERLNREKFFQIEEFLQQINEDIKTKL 268

  Fly   248 --ATWQPHKPSTSGAAVENGHGQQQLPPPPQYANGVDEQIVQTMYQRIVVLEQRTREQETRLENM 310
              :.:...|.:|....|:|                 .:.||....:|...|::...:....:.::
  Fly   269 GNSDYVTSKQATLDYEVKN-----------------VKNIVCETEERCDKLDRALHQTMQNISDL 316

  Fly   311 QKQLRLARQQAPVDPRYSNGTIVWRIEQLGALVARLRANANNQVYSHECYTSPHGYKFCARLNIQ 375
            :.|  :|.||.....:...|.::|||:...   .:|..:.......|....|...:.:..||:|.
  Fly   317 ETQ--MAMQQRIASVQNIRGHLIWRIKDYS---KKLEESKQYDTILHSAMFSNKAFGYALRLDIY 376

  Fly   376 PR-----KPHVLSLHVHLMQSENDYHLDWPFKGRIKLCM----VHPADA--------TLSQHDTI 423
            ..     |...:...::::..|.|..|.||.:.:.::.:    .:.|||        ...:.|..
  Fly   377 LNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDYVKTIFVRKKSDDF 441

  Fly   424 MTKPEILAFHKPREAISTRGF 444
            :...:.  ||.|.:.|::|.:
  Fly   442 IQSNQY--FHIPHKVITSRNY 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	10/48 (21%)
		Sina	163..>230	CDD:302762	19/111 (17%)
		MATH_TRAF6	330..473	CDD:239745	25/132 (19%)
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587	6/33 (18%)
		MATH_TRAF_C	334..473	CDD:238168	25/132 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10131
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910