Protein Alignment Traf6 and Traf2

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001101285.1
• Gene: Traf2 / 311786
• RGDID: 1310457
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 528
• Identity: 112/528 - (21%)
• Similarity: 184/528 - (34%)
• Gaps: 153/528 - (28%)

  Fly    65 ASGAPTPPKSLALNQNHHYAPGSDTS--GEQEEELLDSRYECAICIDWLNEPVLTSCGHRFCRSC 127
            |:.:.|.|.||.|.|     ||...:  |.:    |:::|.|:.|.:.|..|....||||:|..|
  Rat     2 AAASVTSPGSLELLQ-----PGFSKTLLGTR----LEAKYLCSACRNILRRPFQAQCGHRYCSFC 57

  Fly   128 LTAWMQKNNQCCPM--------DNKRLSAEHDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIE 184
            ||:.:....|.|..        :...:......||||..|||:|.|...|||.  ||:...:..|
  Rat    58 LTSILSSGPQNCAACVHEGLYEEGISILESSSAFPDNAARREVESLPAVCPND--GCTWKGTLKE 120

  Fly   185 LHR-HLPSCPY----------------RRQQEPQE------------------------EKCPFA 208
            ... |...||:                ::....||                        |.||..
  Rat   121 YESCHEGLCPFLLTECPACKGLVRLSEKKHHTEQECPKRSLSCQHCRAPCSHADLELHYEVCPKF 185

  Fly   209 KIKCDFVGRP-------------------------------ETNQLEEHLKADMPHHMQLMLQAF 242
            .:.||..|:.                               ||..|::|....:..|:.|:|.:|
  Rat   186 PLTCDGCGKKISQEKLQDHVRTCSKCRVLCRFHAIGCSELVETEDLQDHELQRLREHLALLLSSF 250

  Fly   243 QQTAIATWQPHKPSTSGAAVENGHGQQQLPPPPQYANGVDEQIVQTMYQRIVVLEQRTREQETRL 307
                               :|:...|.|:.|.......:.||.:.|....:.||.:.........
  Rat   251 -------------------LESQASQNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTA 296

  Fly   308 ENMQKQLRLARQQ----------------------APVDPRYS-------NGTIVWRIEQLGALV 343
            |...:|.||.:.:                      |.::.:.|       :|..:|:|.......
  Rat   297 EACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFARKR 361

  Fly   344 ARLRANANNQVYSHECYTSPHGYKFCARLNIQ----PRKPHVLSLHVHLMQSENDYHLDWPFKGR 404
            ....|.....::|...:||.:|||.|.|:.:.    .|..| |||...:|:..||..|.|||..:
  Rat   362 QEAIAGRTPAIFSPAFFTSRYGYKMCLRVYLNGDGTGRGTH-LSLFFVVMKGPNDALLQWPFNQK 425

  Fly   405 IKLCMVHPADATLSQHDTIMTKPEIL--AFHKPREAISTRGFGFLEYANISNI-IQLGFCADDRL 466
            :.|.::   |....:|.....:|::.  :|.:|...::... |...:..:|.| .:..:..||.:
  Rat   426 VTLMLL---DHNNREHVIDAFRPDVTSSSFQRPVSDMNIAS-GCPLFCPVSKIEAKNSYVRDDAI 486

  Fly   467 LIKIEINI 474
            .||..:::
  Rat   487 FIKAIVDL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	14/37 (38%)
		Sina	163..>230	CDD:302762	23/138 (17%)
		MATH_TRAF6	330..473	CDD:239745	37/149 (25%)
Traf2	NP_001101285.1	RING-HC_TRAF2	32..73	CDD:319553	15/40 (38%)
		zf-TRAF	178..234	CDD:280357	9/55 (16%)
		TRAF_BIRC3_bd	265..325	CDD:406958	9/59 (15%)
		MATH_TRAF2	330..493	CDD:239747	39/167 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820