Protein Alignment Traf6 and Traf4

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001100487.1
• Gene: Traf4 / 303285
• RGDID: 1306708
• Length: 470
• Species: Rattus norvegicus
• Alignment Length: 465
• Identity: 102/465 - (21%)
• Similarity: 179/465 - (38%)
• Gaps: 106/465 - (22%)

  Fly   101 RYECAICIDWLNEPV-LTSCGHRFCRSCLTAWMQKNNQCCPMDNKRLSAEHDIFPDNYTRREIEQ 164
            |..|.:|...:.||| :::||||||.:||..::.:....||.|...|... .|:||.....::..
  Rat    15 RLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYA-KIYPDPELEVQVLG 78

  Fly   165 LKRDCPNSSLGCSVVASPIELHRHLPSCPYR-------------RQQEPQ--EEKCPFAKIKCDF 214
            |...|.:|..||........|..||.:|.:.             |:..|.  :..||..::||:|
  Rat    79 LAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEF 143

  Fly   215 VG----------------------------RPETNQLEEHLKADMPHHMQLMLQAFQQTAIATWQ 251
            .|                            |.....|.:|..::.|...|......::....|.|
  Rat   144 CGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQ 208

  Fly   252 PHK----------PSTSGAAVENGHGQQQLPPP-----------------------PQYANGVD- 282
            .|:          |:..|....   .::.||..                       |:.|.|..
  Rat   209 SHQYQCPRLPVPCPNQCGVGTV---AREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRHV 270

  Fly   283 EQIVQTMYQRIVVLEQRTREQETRLENMQKQLRLARQQAPVDPRYSNGTIVWRIEQLGALVARLR 347
            |:.|:.....:..|..|.|::   |:.::::|    ::..|.   |:|.::|:|...|..:...:
  Rat   271 EESVKPHLAMMCALVSRQRQE---LQELRREL----EELSVG---SDGVLIWKIGSYGRRLQEAK 325

  Fly   348 ANANNQVYSHECYTSPHGYKFCARL----NIQPRKPHVLSLHVHLMQSENDYHLDWPFKGRIKLC 408
            |..|.:.:|...||..:|||.....    |......| ||:::.::....|..|:|||..|:...
  Rat   326 AKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTH-LSIYIRVLPGAFDNLLEWPFARRVTFS 389

  Fly   409 MVHPADATLS--QH--DTIMTKPEILAFHKP---REAI--STRGFGFLEYANISNIIQLGFCADD 464
            ::..:|..|:  ||  :|....|....|.||   |.::  |:.|||:.::.:..:|.:..:..||
  Rat   390 LLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDD 454

  Fly   465 RLLIKIEINI 474
            .:.|:..:.:
  Rat   455 AVFIRASVEL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	14/38 (37%)
		Sina	163..>230	CDD:302762	20/109 (18%)
		MATH_TRAF6	330..473	CDD:239745	40/155 (26%)
Traf4	NP_001100487.1	mRING-HC-C3HC3D_TRAF4	15..59	CDD:319555	17/43 (40%)
		zf-TRAF	102..156	CDD:280357	11/53 (21%)
		zf-TRAF	210..269	CDD:280357	8/61 (13%)
		MATH_TRAF4	308..463	CDD:239750	40/155 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810