DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Traf6 and PDZRN4

DIOPT Version :9

Sequence 1:	NP_511080.2	Gene:	Traf6 / 31746	FlyBaseID:	FBgn0265464	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001158067.1	Gene:	PDZRN4 / 29951	HGNCID:	30552	Length:	1036	Species:	Homo sapiens

Alignment Length:	108	Identity:	36/108 - (33%)
Similarity:	52/108 - (48%)	Gaps:	5/108 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 EQEEELLDSRYECAICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCPMDNKRLSAEHDIFPDN 156
            |:..|.:|...||.:|...|.||:.|.|||.||.|||..|..:..: ||:..:.| |..:::...
Human     6 ERFAEAVDPALECKLCGQVLEEPLCTPCGHVFCASCLLPWAVRRRR-CPLQCQPL-APGELYRVL 68

  Fly   157 YTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSC---PYRR 196
            ..|..|::|:..|...:.||.......||..|:..|   |.||
Human    69 PLRSLIQKLRVQCDYRARGCGHSVRLHELEAHVEHCDFGPARR 111

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	17/37 (46%)
		Sina	163..>230	CDD:302762	11/37 (30%)
		MATH_TRAF6	330..473	CDD:239745
PDZRN4	NP_001158067.1	RING	17..54	CDD:238093	17/37 (46%)
		Sina	66..>108	CDD:302762	10/41 (24%)
		PDZ	221..313	CDD:214570
		PDZ_signaling	402..484	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810