DRSC/TRiP Functional Genomics Resources

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Protein Alignment Traf6 and Pdzrn4

DIOPT Version :9

Sequence 1:NP_511080.2 Gene:Traf6 / 31746 FlyBaseID:FBgn0265464 Length:475 Species:Drosophila melanogaster
Sequence 2:NP_001158065.1 Gene:Pdzrn4 / 239618 MGIID:3056996 Length:1014 Species:Mus musculus


Alignment Length:259 Identity:59/259 - (22%)
Similarity:87/259 - (33%) Gaps:70/259 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 EQEEELLDSRYEC-AICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCPMDNKRLSAEHDIFPD 155
            |:..|.:|..::| .:|...|.||..|.|||.||.|||..| ....:.||:..:.| |..:::..
Mouse     6 ERLAEAVDPAFQCQLLCGQVLEEPACTPCGHVFCASCLLPW-AAGRRWCPLQCQPL-APGELYRV 68

  Fly   156 NYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRRQQEPQEEKCP-----FAKIKCDFV 215
            ...|..::||:..|..|..||.        ||....| ::..........|     .|:...:..
Mouse    69 LPLRSLVQQLRVQCNYSGQGCG--------HRGDCGC-WQCTSSAAPSALPAAVTATAQAAAEAA 124

  Fly   216 GRPETNQ---------------------LEEHLKADMPHHMQL-MLQAFQQTAIATWQPHKPSTS 258
            ||..|.:                     |...:........|: :||...|..:|.:..|..:..
Mouse   125 GRKSTRRPRPAGVGTRVRGHPDLEVGLWLSPAVGVGKTRRAQVSLLQRRYQEKLALYMAHTRNFV 189

  Fly   259 GAAVENGHGQQQLPPPPQYANGVDEQIVQTMYQRIVVLEQRTREQET---------RLENMQKQ 313
            |.....|...:|.|                   ..||||   ||.:|         ..:|.|||
Mouse   190 GNPGGRGQDGEQKP-------------------FTVVLE---REDDTLGFNIIGGRPYQNSQKQ 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Traf6NP_511080.2 RING 103..141 CDD:238093 16/38 (42%)
Sina 163..>230 CDD:302762 15/92 (16%)
MATH_TRAF6 330..473 CDD:239745
Pdzrn4NP_001158065.1 RING 18..55 CDD:214546 16/37 (43%)
PDZ 202..294 CDD:214570 12/52 (23%)
PDZ_signaling 383..465 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0297
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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