Protein Alignment Traf6 and Traf1

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001313530.1
• Gene: Traf1 / 22029
• MGIID: 101836
• Length: 409
• Species: Mus musculus
• Alignment Length: 430
• Identity: 88/430 - (20%)
• Similarity: 150/430 - (34%)
• Gaps: 143/430 - (33%)

  Fly    87 SDTSGEQEEELLDSRYEC--AICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCPMDNKRLSAE 149
            :.:|...|.|.   ::.|  |.|.|.....||          |.||.:.:|          |..:
Mouse     2 ASSSAPDENEF---QFGCPPAPCQDPSEPRVL----------CCTACLSEN----------LRDD 43

  Fly   150 HDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRRQQ-----EPQEEKCPFAK 209
            .|               |.||.....        .||...|..|..:::     ...|..||||.
Mouse    44 ED---------------RICPKCRAD--------NLHPVSPGSPLTQEKVHSDVAEAEIMCPFAG 85

  Fly   210 IKCDFVGRPETNQLEEHLKADMPHHMQLMLQAFQQTAIATWQPHKPSTSGA---AVENGHGQQQL 271
            :.|.|.|.|::  ::||.......|:.|:|...::     |:....|..|:   |:|....:.||
Mouse    86 VGCSFKGSPQS--MQEHEATSQSSHLYLLLAVLKE-----WKSSPGSNLGSAPMALERNLSELQL 143

  Fly   272 PPPPQ-----------------------------------------YANGV-------------- 281
            ....:                                         :||.|
Mouse   144 QAAVEATGDLEVDCYRAPCCESQEELALQHLVKEKLLAQLEEKLRVFANIVAVLNKEVEASHLAL 208

  Fly   282 ---------DEQIVQTMYQRIVVLEQRTREQETRLENMQKQLRLARQQAPVDPRYSNGTIVWRIE 337
                     |.:.:.::.||:|.|:|...:::..|..::..||| .::|..|     ||.:|:|.
Mouse   209 AASIHQSQLDREHILSLEQRVVELQQTLAQKDQVLGKLEHSLRL-MEEASFD-----GTFLWKIT 267

  Fly   338 QLGALVARLRANANNQVYSHECYTSPHGYKFCARLNI----QPRKPHVLSLHVHLMQSENDYHLD 398
            .:..............::|...||:.:|||.|.||.:    ..:|.| |||.:.:|:.|.|..|.
Mouse   268 NVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTH-LSLFIVIMRGEYDALLP 331

  Fly   399 WPFKGRIKLCMVHPADATLSQHDTIMTKPEI--LAFHKPR 436
            |||:.::...::   |....:|.....:|::  .:|.:|:
Mouse   332 WPFRNKVTFMLL---DQNNREHAIDAFRPDLSSASFQRPQ 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	10/39 (26%)
		Sina	163..>230	CDD:302762	18/71 (25%)
		MATH_TRAF6	330..473	CDD:239745	30/113 (27%)
Traf1	NP_001313530.1	SMC_prok_B	<126..257	CDD:274008	18/131 (14%)
		TRAF_BIRC3_bd	180..237	CDD:374713	9/56 (16%)
		MATH_TRAF1	260..406	CDD:239748	30/113 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820