Protein Alignment Traf6 and Trim27

DIOPT Version :10

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_033080.2
• Gene: Trim27 / 19720
• MGIID: 97904
• Length: 513
• Species: Mus musculus
• Alignment Length: 318
• Identity: 62/318 - (19%)
• Similarity: 105/318 - (33%)
• Gaps: 116/318 - (36%)

  Fly    96 ELLDSRYECAICIDWLNEPVLTSCGHRFCRSCLT-AW-MQKNNQCCPMDNKRLSAEHDIFPDNYT 158
            |.|.....|.:|:.:..||::..|||..|.:||. .| ..:.|..||..       .:.||..:.
Mouse     8 ECLQQETTCPVCLQYFVEPMMLDCGHNICCACLARCWGAAETNVSCPQC-------RETFPQRHM 65

  Fly   159 R---------REIEQLKRDCPNSSLG----CSVVASPIELHRHLPSCPYRRQQEPQEEKCPFAKI 210
            |         :.::||:.:.|:...|    |.....|::|:     |        ::::.|.. :
Mouse    66 RPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLY-----C--------EQDQMPIC-V 116

  Fly   211 KCDFVGRPETNQLEEHLKADMPHHMQLMLQAFQQTAIATWQPHKPSTSGAAVENGHGQQQLPPPP 275
            .||        :..||                                     .||   .:.|..
Mouse   117 VCD--------RSREH-------------------------------------RGH---SVLPLE 133

  Fly   276 QYANGVDEQIVQTMYQRIVVLEQRTREQETRLENMQKQLRLARQQAPVD----PRYSNGTIVWRI 336
            :...|..|||            |...:...|:::::|:.|...:||..:    .:.....|||..
Mouse   134 EAVEGFKEQI------------QNRLDHLRRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEF 186

  Fly   337 EQL--------GALVARLRA-------NANNQVYSHECYTSPHGYKFCARLNIQPRKP 379
            |||        ..|:|||..       :.|..:....|..| |.....|:|..:.::|
Mouse   187 EQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNIS-HLSGLIAQLEEKQQQP 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	mRING-HC-C3HC3D_LNX1-like	101..143	CDD:438299	14/43 (33%)
		Sina	169..>230	CDD:460824	11/64 (17%)
		MATH_TRAF6	330..473	CDD:239745	17/65 (26%)
Trim27	NP_033080.2	RING-HC_TRIM7-like_C-IV	9..69	CDD:438256	18/66 (27%)
		Bbox2_TRIM7-like	94..137	CDD:380820	12/104 (12%)
		COG4372	<132..>301	CDD:443500	27/125 (22%)
		SPRY_PRY_TRIM27	315..491	CDD:293986