Protein Alignment Traf6 and trf-1

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_499773.2
• Gene: trf-1 / 176767
• WormBaseID: WBGene00006612
• Length: 462
• Species: Caenorhabditis elegans
• Alignment Length: 472
• Identity: 88/472 - (18%)
• Similarity: 155/472 - (32%)
• Gaps: 179/472 - (37%)

  Fly   104 CAICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQ------------------------------- 137
            |.||...|.:|:..:|.|.:||.|    .:..|:
 Worm    18 CPICEQALRDPIKLNCDHHYCRQC----FENENRTPGCAACQTIIQPELCQHDRAKQKQILALPV 78

  Fly   138 -C------CPMDNKRLSAEHDIFPD--------------NYTRREIEQLKRDCPNSSLGCS---- 177
             |      ||.|. :|...||...:              .:.:.::|:.:..|..:...||
 Worm    79 VCTFESSGCPWDG-QLGTLHDHLSECTFKSSLKCEKCGRQFAKNDLEKHRAKCELNRAVCSFCNK 142

  Fly   178 -----------------VVASP----------IELHRHLPSCPYRRQQEPQEEKCPFAKIKCDFV 215
                             :::.|          :|:..|.||||      ..:..|||....|.|.
 Worm   143 TIRDSDRERHPKTCPQVIISCPFQCGLTDRPRLEIEAHCPSCP------NVDNVCPFVPYGCTFA 201

  Fly   216 GRPETNQLEEHLKADMPHHMQLMLQAFQQTAIATWQPHKPSTSGAAVENGHGQQQLPPPPQYANG 280
            |..|:  :::||..:...|:..:........ .|::         .:|...|...
 Worm   202 GGKES--IQQHLSDEPVRHLMYLCDEITDLK-GTYE---------LMERDMGSFN---------- 244

  Fly   281 VDEQIVQTMYQRIVVLEQRTR---EQETRLENMQKQLRLARQQAPVDPRYSNGTIVWRIEQLGAL 342
                            :::||   ..||..|....||                  :|:|::|...
 Worm   245 ----------------DRQTRILSAAETCTEMFGPQL------------------IWKIDKLQQR 275

  Fly   343 VARLRANANNQVYSHECYTSPHGYKF--CARL---NIQPRKPHVLSLHVHLMQSENDYHLDWPFK 402
            ....::.|:..::|....:...|||.  ||.|   .....|.  :||:|.|::.|.|..|:|||.
 Worm   276 TNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKS--ISLYVLLLKGEFDPTLEWPFH 338

  Fly   403 GRIKLCMV----HPADATLSQHDTIMTKPEILAFHKPREAISTR-------GFGFLEYANISNII 456
            ..||:.::    .|.|..   :.|.:..|..|   |..|....|       .||...:.::: |:
 Worm   339 RAIKISLLDQNPRPEDRV---NITYVIDPRKL---KANEKFLARPRGERNAAFGSQSFCSLA-IL 396

  Fly   457 QLGFCADDRLLIKIEIN 473
            | .:..||::.::|:::
 Worm   397 Q-NYVKDDKIYVQIDVD 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	13/74 (18%)
		Sina	163..>230	CDD:302762	20/97 (21%)
		MATH_TRAF6	330..473	CDD:239745	39/158 (25%)
trf-1	NP_499773.2	zf-TRAF	152..210	CDD:280357	14/65 (22%)
		MATH_TRAF_C	264..412	CDD:238168	41/175 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780