Protein Alignment Traf6 and traf3

DIOPT Version :9

• Sequence 1: NP_511080.2
• Gene: Traf6 / 31746
• FlyBaseID: FBgn0265464
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_002938036.2
• Gene: traf3 / 100498216
• XenbaseID: XB-GENE-968262
• Length: 569
• Species: Xenopus tropicalis
• Alignment Length: 589
• Identity: 117/589 - (19%)
• Similarity: 199/589 - (33%)
• Gaps: 192/589 - (32%)

  Fly    43 LSSTGRIAASSSATPSAAAGGGASGAPTPPKSLALNQNHHYAPGSDTSGEQEEEL--LDSRYECA 105
            :..||:....|::...|          .|.:|||..   .|.|  :..|.:|..|  ::.:|:|.
 Frog     8 IMDTGKKTDPSASVQKA----------NPDRSLATT---IYVP--EQGGYKERFLKPVEEKYKCE 57

  Fly   106 ICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCPMDNKRLSAEHDIFPDNYTRREIEQLKRDCP 170
            .|...|..|..|.||||||.:|:.|.:...:..|......::.: .:|.||..|||:..|:..|.
 Frog    58 KCRLVLCNPRQTECGHRFCETCMNAILSSTSPQCMACEDNITKD-KVFKDNCCRREVLALQMFCR 121

  Fly   171 NSSLGCSVVASPIELHRHLPS------------------------------CPYR-------RQQ 198
            |.:.||..:.:...|..||.|                              |.||       |.|
 Frog   122 NETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQ 186

  Fly   199 EP-------QEEKCPFAKIKC-------------------DFVGRPET--------------NQL 223
            .|       ::..||...|.|                   :.|..|.|              .|:
 Frog   187 VPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQQI 251

  Fly   224 EEHLKADMPHHMQLMLQ--AFQQTAIATWQPHKPSTSGAAVENGHGQQ-----QLPPPPQYANGV 281
            :.|..:....|:.||.:  .:.:..::..| ::.|....:::..|.|.     ::....:.....
 Frog   252 KAHEASSAVQHVNLMKEWSNYLEAKVSMLQ-NESSEKNKSIQILHNQMCSFEIEIERHKEQLRNN 315

  Fly   282 DEQIVQTMYQRIVVLEQRTREQETRLENMQKQLRLARQQ-------------------------- 320
            :.:|:|  .||::      ..|..:|:::.|::|..||.
 Frog   316 EARIIQ--LQRVI------EGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQLEVMAK 372

  Fly   321 ----------------------------APVDPRYS-------NGTIVWRIEQLGALVARLRANA 350
                                        |.:|.|:.       ||.::|:|..............
 Frog   373 NAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGK 437

  Fly   351 NNQVYSHECYTSPHGYKFCARLNI----QPRKPHVLSLHVHLMQSENDYHLDWPFKGRIKLCMVH 411
            ...:||...||...|||.|||:.:    ..:..| |||...:|:.|.|..|.||||.::.|.::.
 Frog   438 TLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTH-LSLFFVIMRGEYDALLPWPFKQKVSLMLMD 501

  Fly   412 PADATLSQHDTIMTKPEILAFHKPREAISTRGFGFLEYAN------ISNIIQLG-FCADDRLLIK 469
            ...:.....|.....|...:|.||.        |.:..|:      ...:::.| :..||.:.||
 Frog   502 QGPSRRHLGDAFKPDPNSSSFKKPT--------GEMNIASGCPVFVAQTVLENGTYIKDDTIFIK 558

  Fly   470 IEIN 473
            :.::
 Frog   559 VIVD 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf6	NP_511080.2	RING	103..141	CDD:238093	14/37 (38%)
		Sina	163..>230	CDD:302762	24/143 (17%)
		MATH_TRAF6	330..473	CDD:239745	38/153 (25%)
traf3	XP_002938036.2	RING-HC_TRAF3	54..95	CDD:319554	15/40 (38%)
		RING-HC finger (C3HC4-type)	56..94	CDD:319554	14/37 (38%)
		zf-TRAF	139..195	CDD:280357	9/55 (16%)
		zf-TRAF	200..250	CDD:280357	7/49 (14%)
		Smc	<255..>372	CDD:224117	17/125 (14%)
		MATH_TRAF3	382..564	CDD:239746	42/190 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391991at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49412
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920