DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18262 and ZNF132

DIOPT Version :9

Sequence 1:NP_572453.1 Gene:CG18262 / 31745 FlyBaseID:FBgn0030012 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_003424.3 Gene:ZNF132 / 7691 HGNCID:12916 Length:706 Species:Homo sapiens


Alignment Length:483 Identity:122/483 - (25%)
Similarity:192/483 - (39%) Gaps:106/483 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 GGYHNLRCGEVLFSAPASYEVSCLLCDQRLPLDGYPEHFRLKHFTNSSSSLCSNELESDPIAQDV 76
            |.:|.:. ||   .|.....||..:...|:| :..|...:.     :|..:|.      |..:|:
Human    78 GSWHGVE-GE---GAHPKQNVSVEVLQVRIP-NADPSTKKA-----NSCDMCG------PFLKDI 126

  Fly    77 VEVQGNEELHEELAKEASP--------------DLEEEEEEKEEGSKRQHYQ-RAAAMKNTLVET 126
            :.:..    |:....|..|              :|.:.::|...|...:.|: |.|.||::.|..
Human   127 LHLAE----HQGTQSEEKPYTCGACGRDFWLNANLHQHQKEHSGGKPFRWYKDRDALMKSSKVHL 187

  Fly   127 RE----------------DLLDIELDWTG-------GEQSE------------------------ 144
            .|                |||.::...:|       |:..|                        
Human   188 SENPFTCREGGKVILGSCDLLQLQAVDSGQKPYSNLGQLPEVCTTQKLFECSNCGKAFLKSSTLP 252

  Fly   145 -HNETHEEE-------EGESDDDDTKDSN---DTKDMLFQCDQCDRAYNTKRSLQSHRRLKHSE- 197
             |..||.||       .|...::.:...|   .|.::...|.:|.:|::....|:.|::. |:| 
Human   253 NHLRTHSEEIPFTCPTGGNFLEEKSILGNKKFHTGEIPHVCKECGKAFSHSSKLRKHQKF-HTEV 316

  Fly   198 ------ANGGSLDKSASERNSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWKHTG---IFCDI 253
                  |.|.:.:...:..:.::.....:.|:|:|  |.:.|.....|..|...|||   ..|..
Human   317 KYYECIACGKTFNHKLTFVHHQRIHSGERPYECDE--CGKAFSNRSHLIRHEKVHTGERPFECLK 379

  Fly   254 CGKPFTQSGNMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCRDRG 318
            ||:.|:||.|.:||::.|:.::|::|.:|..:|.....|..|...|||..|..|..|||...:..
Human   380 CGRAFSQSSNFLRHQKVHTQVRPYECSQCGKSFSRSSALIQHWRVHTGERPYECSECGRAFNNNS 444

  Fly   319 VLTAHMRRHTGERPAKCEVCGKAFYSFHDLNVHAVSHTNLRPFVCDVCGSTFQRKKALRVHKLLH 383
            .|..|.:.||||||.:|..||:.|.....|..|...||..|||.|..||..|.....|..|:.:|
Human   445 NLAQHQKVHTGERPFECSECGRDFSQSSHLLRHQKVHTGERPFECCDCGKAFSNSSTLIQHQKVH 509

  Fly   384 SEQRKYACKLCGKTFAQSGGLNAHMRSH 411
            :.||.|.|..|.|:|::|..|..|.|.|
Human   510 TGQRPYECSECRKSFSRSSSLIQHWRIH 537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18262NP_572453.1 C2H2 Zn finger 224..246 CDD:275368 6/21 (29%)
C2H2 Zn finger 251..271 CDD:275368 9/19 (47%)
COG5048 <256..415 CDD:227381 59/156 (38%)
zf-H2C2_2 263..288 CDD:290200 8/24 (33%)
C2H2 Zn finger 279..327 CDD:275368 15/47 (32%)
zf-H2C2_2 320..342 CDD:290200 11/21 (52%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
C2H2 Zn finger 363..383 CDD:275368 6/19 (32%)
zf-C2H2 389..411 CDD:278523 9/21 (43%)
C2H2 Zn finger 391..411 CDD:275368 8/19 (42%)
ZNF132NP_003424.3 KRAB 37..78 CDD:307490 122/483 (25%)
COG5048 105..528 CDD:227381 108/440 (25%)
C2H2 Zn finger 116..136 CDD:275368 4/29 (14%)
C2H2 Zn finger 144..164 CDD:275368 1/19 (5%)
C2H2 Zn finger 238..285 CDD:275368 7/46 (15%)
C2H2 Zn finger 293..313 CDD:275368 5/20 (25%)
C2H2 Zn finger 321..341 CDD:275368 2/19 (11%)
C2H2 Zn finger 349..369 CDD:275368 6/21 (29%)
C2H2 Zn finger 377..397 CDD:275368 9/19 (47%)
COG5048 383..>706 CDD:227381 59/155 (38%)
C2H2 Zn finger 405..425 CDD:275368 5/19 (26%)
C2H2 Zn finger 433..453 CDD:275368 6/19 (32%)
C2H2 Zn finger 461..481 CDD:275368 6/19 (32%)
C2H2 Zn finger 489..509 CDD:275368 6/19 (32%)
C2H2 Zn finger 517..537 CDD:275368 8/19 (42%)
C2H2 Zn finger 545..565 CDD:275368
C2H2 Zn finger 573..593 CDD:275368
C2H2 Zn finger 601..621 CDD:275368
C2H2 Zn finger 629..649 CDD:275368
C2H2 Zn finger 657..677 CDD:275368
C2H2 Zn finger 685..705 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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