DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18262 and Sry-beta

DIOPT Version :9

Sequence 1:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	87/425 - (20%)
Similarity:	153/425 - (36%)	Gaps:	126/425 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 CLLCDQRLPLDGYPEHF------RLKHFTNSSSSLCSNELE----SDPIAQDVVEVQGNEELHEE 88
            |::.....|:....::|      ||:...||::  |.:.||    .|.:.:::.:||  .::.:.
  Fly    26 CIVPGTFKPIKDILKYFEKIINQRLELLPNSAA--CRDCLEYLFNYDRLVRNLSQVQ--RQIADA 86

  Fly    89 LAKEASPDLEEEEEEKEEGSKRQHYQ-------RAAAMKNTLVETREDLLDIELDWTGGEQSEHN 146
            |.  ....:|.:.|.|::.:||...|       :|.|:|             |.:...||:.|..
  Fly    87 LL--GCRQVEGKAETKQQAAKRARVQVPAFKIVQATALK-------------EPERQPGEEDECE 136

  Fly   147 ETHEEEEGE-----SDDDDTKDSND----TKDMLFQCDQCDRAYNTKRSLQSHRRLKHSEANGGS 202
            |..:||..:     |:.||:..|::    |:.....|..|...::::..|:     :|.:|:...
  Fly   137 EFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFSSQEVLE-----RHIKADTCQ 196

  Fly   203 LDKSASERNSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWKHTG---IFCDICGKPFTQSGNM 264
            ..:.|:               ||  .|....:.:..|..|...|.|   :.|..|.|.|:...|:
  Fly   197 KSEQAT---------------CN--VCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNV 244

  Fly   265 MRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCRDRGVLTAHMRRHTG 329
            :||.:.|...|.::|.:|...|    .||                        .::..|:.||..
  Fly   245 LRHMEVHWDKKKYQCDKCGERF----SLS------------------------WLMYNHLMRHDA 281

  Fly   330 ERPAKCEVCGKAFYSFHDLNVHAVSHTNLRPFVCDVCGSTFQRKKALRVHKLLHSEQR-KYACKL 393
            |..|                           .:|:||...|:.|:..:.|...|...| :|.|..
  Fly   282 EENA---------------------------LICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPD 319

  Fly   394 CGKTFAQSGGLNAHMRSHDPARVKGAVKPLPQSVT 428
            |.|:|.....|..|.|.|.|.....:.:....:||
  Fly   320 CEKSFVDKYTLKVHKRVHQPVEKPESAEAKEATVT 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	5/21 (24%)
		C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		COG5048	<256..415	CDD:227381	35/159 (22%)
		zf-H2C2_2	263..288	CDD:290200	8/24 (33%)
		C2H2 Zn finger	279..327	CDD:275368	6/47 (13%)
		zf-H2C2_2	320..342	CDD:290200	5/21 (24%)
		C2H2 Zn finger	335..355	CDD:275368	0/19 (0%)
		C2H2 Zn finger	363..383	CDD:275368	6/19 (32%)
		zf-C2H2	389..411	CDD:278523	8/21 (38%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	5/21 (24%)
		C2H2 Zn finger	231..251	CDD:275368	7/19 (37%)
		C2H2 Zn finger	259..308	CDD:275368	16/103 (16%)
		C2H2 Zn finger	288..303	CDD:275370	5/14 (36%)
		zf-C2H2	315..337	CDD:278523	8/21 (38%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449773
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930