DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18262 and CG7963

DIOPT Version :9

Sequence 1:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_649798.3	Gene:	CG7963 / 41001	FlyBaseID:	FBgn0037584	Length:	354	Species:	Drosophila melanogaster

Alignment Length:	415	Identity:	87/415 - (20%)
Similarity:	149/415 - (35%)	Gaps:	93/415 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 APASYEVSCLLCDQRLPLDGYPEHFRLKHFTNSSSSLCSNELESDPIAQDVVEVQGNEELHEELA 90
            :|.|.|..|.:|                             |:.|.:..|:.|:.  ||:..:|.
  Fly     2 SPPSGEFRCRVC-----------------------------LKQDELLVDIYEIV--EEMQVDLC 35

  Fly    91 K--EASPDLEEEEEEKEEGSKRQHYQR----AAAMKNTLVET---REDLLDIELDWTGGEQSEH- 145
            .  |....::.:..:.:.....|....    ||..:...||:   |:...:|.:|......||.
  Fly    36 TLLETCGGIKVDRRDVQPMYLCQECTNELLIAAKFRKICVESEKLRDMAPEINIDTAEPLASEEI 100

  Fly   146 ----NETHEEEEGESDDDDTKDSNDTKDMLFQCDQCDRAYNTKRSLQSHRRLKHSEANGGSLDKS 206
                ...:.|:....:|.:.:....::   :.|..|...:.....|:.|.:..|:...  .:|..
  Fly   101 IIIDPSDYIEQLSAVEDPENEPIGVSR---WNCQHCGAGFQLSEVLRRHIQEVHASIT--IIDCR 160

  Fly   207 ASER-----------NSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWKHTG---IFCDICGKP 257
            ...|           |....|.|.:.:||.|  |.:..::...|..|...||.   ..||.|.|.
  Fly   161 ERRRIFTKLGCYQVHNCSYAKTPKRGHKCLE--CGKCLQSASSLASHIRLHTDEWPFTCDQCAKA 223

  Fly   258 FTQSGNMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCRDRGVLTA 322
            |..:|.:..|::||..:..|||..|...|.....|..|.:
  Fly   224 FRTNGALEVHQRRHKQVLQHKCLHCGRGFVESSNLRRHIV------------------------- 263

  Fly   323 HMRRHTGERPAKCEVCGKAFYSFHDLNVHAVSHTNLRPFVCDVCGSTFQRKKALRVHKLLHSEQR 387
              .|||.|||..|.|..::|...:.|.:|..::|..||:.|......|.:...|::|:.:|:.:|
  Fly   264 --NRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHRDKRFAQLGVLKIHERIHTGER 326

  Fly   388 KYACKLCGKTFAQSGGLNAHMRSHD 412
            .:.|::|.|.|.::|.|..|...|:
  Fly   327 LHRCQVCEKPFTRAGQLRKHALRHE 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	5/21 (24%)
		C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		COG5048	<256..415	CDD:227381	41/157 (26%)
		zf-H2C2_2	263..288	CDD:290200	8/24 (33%)
		C2H2 Zn finger	279..327	CDD:275368	5/47 (11%)
		zf-H2C2_2	320..342	CDD:290200	8/21 (38%)
		C2H2 Zn finger	335..355	CDD:275368	5/19 (26%)
		C2H2 Zn finger	363..383	CDD:275368	4/19 (21%)
		zf-C2H2	389..411	CDD:278523	7/21 (33%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
CG7963	NP_649798.3	zf-AD	10..80	CDD:285071	15/100 (15%)
		C2H2 Zn finger	159..179	CDD:275368	2/19 (11%)
		COG5048	184..>250	CDD:227381	21/67 (31%)
		C2H2 Zn finger	189..209	CDD:275368	5/21 (24%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		C2H2 Zn finger	245..262	CDD:275368	4/16 (25%)
		C2H2 Zn finger	274..294	CDD:275368	5/19 (26%)
		C2H2 Zn finger	302..322	CDD:275368	4/19 (21%)
		zf-H2C2_2	315..339	CDD:290200	8/23 (35%)
		C2H2 Zn finger	330..350	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BQ0F
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900