DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18262 and CG11247

DIOPT Version :9

Sequence 1:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	90/314 - (28%)
Similarity:	133/314 - (42%)	Gaps:	37/314 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 KNTLVETREDLLDIELDWTGGEQSEHNETHEEEEGESDDDD---------TKDSNDTKDMLFQCD 175
            |::|...|:..:|.|.| .||||            :|.|||         .:.....|.....|.
  Fly    45 KSSLASLRDACVDEEED-DGGEQ------------DSKDDDYVQPQLKKSARKGEPVKRKHHVCS 96

  Fly   176 QCDRAYNTKRSLQSHRRLKHSEANGGSLDKSASERNSKKRKG-------PPKVYKCNEEACNQTF 233
            ||.:.:..|..||.|..:...|......|...|.|.:...|.       ..|.:.|::  |.::|
  Fly    97 QCSKEFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAVNLKNHITTAHEHRKQFVCSQ--CPKSF 159

  Fly   234 RTERDLRGHRWKHTG---IFCDICGKPFTQSGNMMRHRQRH--SGIKPHKCPECDATFYTQKELS 293
            ..:..||.|...|:|   ..||:|.|.|.:.|.:.:|...|  :.|:...|.:|.|:|.|...|.
  Fly   160 ALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTNANLR 224

  Fly   294 SHSICHTGRMPCICEVCGRPCRDRGVLTAHM-RRHTGERPAKCEVCGKAFYSFHDLNVHAVSHTN 357
            .|...|...|...|.:|.....:...|.||: :.|......:||:|.|......||..|...||.
  Fly   225 VHMERHEQGMEHRCSICENQFANELALRAHINQEHHKLTQFECEICHKMIEPDEDLATHMQRHTA 289

  Fly   358 LRPFVCDVCGSTFQRKKALRVHKLLHSEQRKYACKLCGKTFAQSGGLNAHMRSH 411
            ::..||:||.:.|.:|....||..:|:.:|.|.|::|.:|||.|..|..|:|.|
  Fly   290 VKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKH 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	6/21 (29%)
		C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		COG5048	<256..415	CDD:227381	51/159 (32%)
		zf-H2C2_2	263..288	CDD:290200	7/26 (27%)
		C2H2 Zn finger	279..327	CDD:275368	14/48 (29%)
		zf-H2C2_2	320..342	CDD:290200	8/22 (36%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	7/19 (37%)
		zf-C2H2	389..411	CDD:278523	10/21 (48%)
		C2H2 Zn finger	391..411	CDD:275368	9/19 (47%)
CG11247	NP_001097659.1	COG5048	<88..247	CDD:227381	42/160 (26%)
		C2H2 Zn finger	95..115	CDD:275368	7/19 (37%)
		zf-H2C2_2	107..132	CDD:290200	6/24 (25%)
		C2H2 Zn finger	123..144	CDD:275368	4/20 (20%)
		C2H2 Zn finger	152..172	CDD:275368	6/21 (29%)
		zf-H2C2_2	165..189	CDD:290200	10/23 (43%)
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		COG5048	<192..369	CDD:227381	48/152 (32%)
		C2H2 Zn finger	210..230	CDD:275370	7/19 (37%)
		C2H2 Zn finger	238..260	CDD:275371	5/21 (24%)
		C2H2 Zn finger	267..287	CDD:275368	7/19 (37%)
		C2H2 Zn finger	295..315	CDD:275368	7/19 (37%)
		zf-H2C2_2	309..332	CDD:290200	9/22 (41%)
		C2H2 Zn finger	323..343	CDD:275368	9/19 (47%)
		C2H2 Zn finger	351..374	CDD:275368
		C2H2 Zn finger	382..399	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446627
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840