DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG18262 and pita

DIOPT Version :9

Sequence 1:NP_572453.1 Gene:CG18262 / 31745 FlyBaseID:FBgn0030012 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_611806.3 Gene:pita / 37730 FlyBaseID:FBgn0034878 Length:683 Species:Drosophila melanogaster


Alignment Length:364 Identity:86/364 - (23%)
Similarity:148/364 - (40%) Gaps:95/364 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 VEVQGNEELH----EELAKEASPDLEEEEEEKEEGSKRQHYQRAAAMKNTL-------------- 123
            ::|..|:||.    :.:.::.:.:||:|..:..        |:|:.:|..:              
  Fly   179 LKVDNNQELSMDDVQSMLEDMASELEKEFPDIP--------QKASPVKPKVLNKSSIRILNKGPA 235

  Fly   124 --VETREDLLDIELDWTGGEQSEHNETHEEEEGESD------DDDTKDSNDTKDMLFQCDQCDRA 180
              ||.|.....::.|.:|      |.....|..:||      ||.||::......:|.|..|:|:
  Fly   236 APVEPRLATPKVKRDDSG------NVAIVTEVLDSDLPLDDQDDPTKNAEKVATDVFPCPDCERS 294

  Fly   181 YNTKRSLQSHRRLKHSEANGGSLDKSASERNSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWK 245
            :..::.|:.| ||.|:.:                     :.::|  ..|.::|.::.||..|.:.
  Fly   295 FPLQQLLEIH-RLNHTRS---------------------RSFQC--LLCEKSFFSKYDLAKHNFV 335

  Fly   246 HTG---IFCDICGKPFTQSGNMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCIC 307
            |||   ..|.||.|.||:...:.||.:.|:.:....|..|:..|.:::|:..|:           
  Fly   336 HTGERPFKCAICSKAFTRKALLHRHERTHTDVPKFICVYCEKPFLSRQEMEKHA----------- 389

  Fly   308 EVCGRPCRDRGVLTAHMRRHTGERPAKCEVCGKAFYSFHDLNVHAVSHTNLRPFVCDVCGSTFQR 372
                             .||..:||.:|.||.|:|.....|..|...|:...||.|..|..:|..
  Fly   390 -----------------ERHQKKRPFQCGVCTKSFAFKQGLERHETVHSTNLPFPCQHCERSFST 437

  Fly   373 KKALRVHKLLHSEQRKYACKLCGKTFAQSGGLNAHMRSH 411
            ...|..|.:.|:.:|.|.||.|.|::..|..|:.|:|:|
  Fly   438 ASKLARHLVAHAGKRAYPCKYCHKSYMLSHHLSRHLRTH 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18262NP_572453.1 C2H2 Zn finger 224..246 CDD:275368 6/21 (29%)
C2H2 Zn finger 251..271 CDD:275368 8/19 (42%)
COG5048 <256..415 CDD:227381 42/156 (27%)
zf-H2C2_2 263..288 CDD:290200 6/24 (25%)
C2H2 Zn finger 279..327 CDD:275368 5/47 (11%)
zf-H2C2_2 320..342 CDD:290200 8/21 (38%)
C2H2 Zn finger 335..355 CDD:275368 7/19 (37%)
C2H2 Zn finger 363..383 CDD:275368 5/19 (26%)
zf-C2H2 389..411 CDD:278523 9/21 (43%)
C2H2 Zn finger 391..411 CDD:275368 8/19 (42%)
pitaNP_611806.3 zf-AD 17..92 CDD:214871
COG5048 <281..506 CDD:227381 63/248 (25%)
C2H2 Zn finger 288..308 CDD:275368 7/20 (35%)
C2H2 Zn finger 316..336 CDD:275368 6/21 (29%)
zf-H2C2_2 328..353 CDD:290200 11/24 (46%)
C2H2 Zn finger 344..364 CDD:275368 8/19 (42%)
C2H2 Zn finger 372..388 CDD:275370 4/15 (27%)
C2H2 Zn finger 400..420 CDD:275368 7/19 (37%)
C2H2 Zn finger 428..448 CDD:275368 5/19 (26%)
C2H2 Zn finger 456..476 CDD:275368 8/19 (42%)
C2H2 Zn finger 486..506 CDD:275368
HARE-HTH <566..625 CDD:294801
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45449758
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24390
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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