DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18262 and CG12391

DIOPT Version :9

Sequence 1:NP_572453.1 Gene:CG18262 / 31745 FlyBaseID:FBgn0030012 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_610639.1 Gene:CG12391 / 36170 FlyBaseID:FBgn0033581 Length:587 Species:Drosophila melanogaster


Alignment Length:507 Identity:99/507 - (19%)
Similarity:164/507 - (32%) Gaps:175/507 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 SNELESDPIAQDVVEVQGNEELHEELAKEASPDLEEEEEEKEEGSKRQHYQRAAAMKNTLVETRE 128
            |.|...:...:|..:.:....|||:...:|..|.:|.:.|.|:..::...:......:..:|..|
  Fly   119 SKEKSGEDGEKDTDKEKKATHLHEDNNDDAEKDGDEADAEDEDDVEKPEDEDGTEEGDEAIEEDE 183

  Fly   129 DLLD-----------IELDWTGGEQSEHNETHEEEEGESDD--------DDTKDSNDTK------ 168
            |.||           ||.|:..|..:|......:|.|:..|        ::..|.:..:      
  Fly   184 DALDEDEDPNEEVEEIEPDFETGTDAEGELITGDEPGDLADVPIRERKKEEPVDEDQCRVCTSKE 248

  Fly   169 ---------------DML-----------------FQCDQC----DRAYNTKRSLQS-----HRR 192
                           |||                 |.|.:|    ..|...::.|::     .:|
  Fly   249 ELVCLFKKQIDATPADMLLVICPNVSILPKDFMPQFICTKCMGSLTIAIQLRKQLETTDQELRKR 313

  Fly   193 LKHSE----------------------------------------ANGGSLDKSASERNSKK--- 214
            |..|:                                        |:..|.|...||:..||   
  Fly   314 LSRSKNKVRRPRGYVVIDAPVTDSSEDEDELDDEFKVSDVAGTTSADSDSADSDDSEKEKKKPGP 378

  Fly   215 ----RKGPPKVYKCNEEACNQTFRTERDLRGHRWKHTGIFCDICGKPFTQSGNMMRHR-QRHSGI 274
                ||.|.|                   ||         .|..|:|  .|....::: ...:.:
  Fly   379 RGRPRKKPLK-------------------RG---------TDSDGEP--SSAQKKKYQPSSTASV 413

  Fly   275 KPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCRDRGVLTAHMRRHTGERP-AKCEVC 338
            .|.:||.||.||..::....|...|. |:...|.:||:..:.......||:||..||. .:||:|
  Fly   414 GPFECPNCDLTFSRKQSYVLHRKTHE-RIEHACPICGKKFKVEWAYKTHMQRHEQERAHFRCELC 477

  Fly   339 GKAFYSFHDLNVHAVSHTNLRPFV--CDVCGSTFQRKKALRVHKL------------LHSEQRKY 389
            .|.|....:|..|.....:...|:  |..|..||..::.|:.|:.            :..||.::
  Fly   478 PKIFRLRAELKHHMAQRHDEHGFIYECKRCQRTFLTQQRLQRHQAVGCQRHKEDSVRIKEEQSRF 542

  Fly   390 ACKLCGKTFAQSGGLNAHMRSHDPARVKGAVKPLPQSVTIEVIEGKSPPTTT 441
            ..:...|.       :.|..::...|..|..:.|.::|        :|||||
  Fly   543 KQESRSKD-------DRHHGNNSSKRRPGEGRDLFKAV--------APPTTT 579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18262NP_572453.1 C2H2 Zn finger 224..246 CDD:275368 2/21 (10%)
C2H2 Zn finger 251..271 CDD:275368 4/20 (20%)
COG5048 <256..415 CDD:227381 39/174 (22%)
zf-H2C2_2 263..288 CDD:290200 7/25 (28%)
C2H2 Zn finger 279..327 CDD:275368 14/47 (30%)
zf-H2C2_2 320..342 CDD:290200 10/22 (45%)
C2H2 Zn finger 335..355 CDD:275368 7/19 (37%)
C2H2 Zn finger 363..383 CDD:275368 6/31 (19%)
zf-C2H2 389..411 CDD:278523 2/21 (10%)
C2H2 Zn finger 391..411 CDD:275368 2/19 (11%)
CG12391NP_610639.1 zf-AD 240..313 CDD:285071 8/72 (11%)
zf-C2H2 416..438 CDD:278523 7/21 (33%)
C2H2 Zn finger 418..438 CDD:275368 7/19 (37%)
zf-C2H2 443..465 CDD:278523 5/21 (24%)
C2H2 Zn finger 445..465 CDD:275368 5/19 (26%)
C2H2 Zn finger 474..491 CDD:275368 6/16 (38%)
C2H2 Zn finger 504..521 CDD:275368 5/16 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24390
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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