DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18262 and CG15436

DIOPT Version :9

Sequence 1:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	96/343 - (27%)
Similarity:	139/343 - (40%)	Gaps:	36/343 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 IAQDVVEVQGNEELHEELAKEASPDLEEEEEEKEEGSKR---QHYQRAAAMKNTLVETREDLLDI 133
            ||:.:.:..|.|....:|..|.......|:.:...|.::   :.:|....:::..:|.....|..
  Fly    29 IAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIRQTCEESHQFYCRVRDEGIEDALCALLE 93

  Fly   134 ELDWTGGEQSEHNETHEEEEGESDDDDTKDSNDTKDMLFQCDQCDRAYNTKRSLQSHRRLKHSEA 198
            |.||   |.||..:...:....:|||...||   |.:.|:|.:|.:.|..|.:...|.|   :..
  Fly    94 EEDW---EISEDEDARIDSASAADDDGKSDS---KKVAFECRECHKKYQRKGTFLRHMR---THM 149

  Fly   199 NGGSLDKSASERNSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWKHTG---IFCDICGKPFTQ 260
            :|.|.               |..|      |.:.||....|:.|...|..   ..|..|.|.|.|
  Fly   150 DGQSF---------------PCPY------CKRNFRLRVTLKAHMKTHNAAKPYECSHCAKTFAQ 193

  Fly   261 SGNMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCRDRGVLTAHMR 325
            ...:..|.:.|:|.:|.||.:|..||....:|..|...|....|..|..|.:....:..|..|.|
  Fly   194 QSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFR 258

  Fly   326 RHTGERPAKCEVCGKAFYSFHDLNVHAVSHTNLRPFVCDVCGSTFQRKKALRVHKLLHSEQRKYA 390
            .||||||.||..|.|||.....|..|:..|...|||.|..|..||:....|:.|||:|:.:|.:.
  Fly   259 SHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFK 323

  Fly   391 CKLCGKTFAQSGGLNAHM 408
            |..|...:.|...|..|:
  Fly   324 CPHCASFYKQRKTLARHI 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	5/21 (24%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		COG5048	<256..415	CDD:227381	54/153 (35%)
		zf-H2C2_2	263..288	CDD:290200	9/24 (38%)
		C2H2 Zn finger	279..327	CDD:275368	13/47 (28%)
		zf-H2C2_2	320..342	CDD:290200	13/21 (62%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	8/19 (42%)
		zf-C2H2	389..411	CDD:278523	5/20 (25%)
		C2H2 Zn finger	391..411	CDD:275368	5/18 (28%)
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071	9/48 (19%)
		C2H2 Zn finger	128..148	CDD:275368	6/22 (27%)
		C2H2 Zn finger	156..176	CDD:275368	6/25 (24%)
		COG5048	<180..341	CDD:227381	55/160 (34%)
		C2H2 Zn finger	184..204	CDD:275368	6/19 (32%)
		zf-H2C2_2	197..219	CDD:290200	7/21 (33%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		zf-H2C2_2	224..249	CDD:290200	6/24 (25%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-H2C2_2	252..276	CDD:290200	14/23 (61%)
		C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		C2H2 Zn finger	296..316	CDD:275368	8/19 (42%)
		C2H2 Zn finger	324..341	CDD:275368	4/16 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940