DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18262 and Zfp62

DIOPT Version :9

Sequence 1:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001349654.1	Gene:	Zfp62 / 22720	MGIID:	99662	Length:	914	Species:	Mus musculus

Alignment Length:	430	Identity:	114/430 - (26%)
Similarity:	183/430 - (42%)	Gaps:	73/430 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LKHFTNSSSSLCSNELESDPIAQDVVEVQGNEELHEELAKEASPDLEEEEEEKEEGS-------- 108
            ::...::.::..:.:||.|....:.........:|:.:..|.:...:.|..|...|:
Mouse    63 IREMIDTHTNAANIKLEQDDETSEKSFYPSTNTMHQTIPTEPNCTKQGEHTENINGNVHPAHIAD 127

  Fly   109 KRQH---------YQRAAAMKNTLVETREDLLDIELDWTGGEQSE-----HNETHEEEEGESDDD 159
            |:.|         ...:..:::.::.|.|...:.: |..|..:|.     |...|..|:....|:
Mouse   128 KKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECD-DCRGTFRSSSSLRVHKRIHTGEKPYKCDE 191

  Fly   160 DTK-----------DSNDTKDMLFQCDQCDRAYNTKRSLQSHRRLKHSEAN------GGSLDKSA 207
            ..|           .|..:.:...:||:|.:::|....|..|:|:...|..      |.:...|:
Mouse   192 CGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSS 256

  Fly   208 SERNSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWKHTG---IFCDICGKPFTQSGNMMRHRQ 269
            ..|..|:.....|.|:|  :.|.:||.....||.|:..|||   ..||.|||.|.....::.|:.
Mouse   257 GLRVHKRIHTGEKPYEC--DTCGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKS 319

  Fly   270 RHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCRDRGVLTAHMRRHTGERPAK 334
            .|.|.||:||.||:.:|.....|..|.:.|||..|..|:.||:..|:...|..|.|.||||:|.|
Mouse   320 IHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYK 384

  Fly   335 CEVCGKAF---------------------------YSFHDLNV-HAVSHTNLRPFVCDVCGSTFQ 371
            |::|||||                           :|::.|.: |...||..||:||||||.||:
Mouse   385 CDICGKAFSYSSGLAVHKSIHPGKKAHECKDCGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFR 449

  Fly   372 RKKALRVHKLLHSEQRKYACKLCGKTFAQSGGLNAHMRSH 411
            ....|:||:.||:.::.|.|.:|||.:.....|..|...|
Mouse   450 NNSGLKVHRRLHTGEKPYKCDVCGKAYISRSSLKNHKGIH 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	7/21 (33%)
		C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		COG5048	<256..415	CDD:227381	65/184 (35%)
		zf-H2C2_2	263..288	CDD:290200	10/24 (42%)
		C2H2 Zn finger	279..327	CDD:275368	17/47 (36%)
		zf-H2C2_2	320..342	CDD:290200	13/21 (62%)
		C2H2 Zn finger	335..355	CDD:275368	9/47 (19%)
		C2H2 Zn finger	363..383	CDD:275368	10/19 (53%)
		zf-C2H2	389..411	CDD:278523	7/21 (33%)
		C2H2 Zn finger	391..411	CDD:275368	6/19 (32%)
Zfp62	NP_001349654.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..101		2/20 (10%)
		COG5048	127..542	CDD:227381	106/366 (29%)
		C2H2 Zn finger	133..153	CDD:275368	0/19 (0%)
		C2H2 Zn finger	161..181	CDD:275368	4/20 (20%)
		C2H2 Zn finger	189..209	CDD:275368	3/19 (16%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		C2H2 Zn finger	245..265	CDD:275368	4/19 (21%)
		C2H2 Zn finger	273..293	CDD:275368	7/21 (33%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
		C2H2 Zn finger	329..349	CDD:275368	6/19 (32%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		SFP1	<379..458	CDD:227516	27/78 (35%)
		C2H2 Zn finger	385..405	CDD:275368	6/19 (32%)
		C2H2 Zn finger	413..433	CDD:275368	3/19 (16%)
		COG5048	437..850	CDD:227381	23/53 (43%)
		C2H2 Zn finger	441..461	CDD:275368	10/19 (53%)
		C2H2 Zn finger	469..489	CDD:275368	6/19 (32%)
		C2H2 Zn finger	497..517	CDD:275368
		C2H2 Zn finger	525..545	CDD:275368
		C2H2 Zn finger	553..573	CDD:275368
		C2H2 Zn finger	581..601	CDD:275368
		C2H2 Zn finger	609..629	CDD:275368
		C2H2 Zn finger	637..657	CDD:275368
		C2H2 Zn finger	665..685	CDD:275368
		C2H2 Zn finger	693..713	CDD:275368
		C2H2 Zn finger	721..741	CDD:275368
		C2H2 Zn finger	749..769	CDD:275368
		C2H2 Zn finger	777..797	CDD:275368
		C2H2 Zn finger	805..824	CDD:275368
		C2H2 Zn finger	832..852	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000