DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18262 and M03D4.4

DIOPT Version :9

Sequence 1:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001023313.1	Gene:	M03D4.4 / 177375	WormBaseID:	WBGene00019751	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	317	Identity:	84/317 - (26%)
Similarity:	129/317 - (40%)	Gaps:	59/317 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 LFQCDQCDRAYNTKRSLQSHRRLKHSEANGGSLDKSASERNSK-----KRKGPPKVYKCNEE--- 227
            |:.|..|..|:::...||.|.|.:|.....|..::...|.:|.     |.|.....:..:.:
Worm     4 LYLCRDCSGAFHSLDELQRHEREEHETVEQGDQEEDRMEDDSDELAMIKIKIEDSDFLSDTDSSQ 68

  Fly   228 -ACNQTFRTERDLRGHRWKHTGIFCDICGKPFTQSGNMMRHRQRHSGIKPHKCPECDATFYTQKE 291
             :.|.|..:|:...|.:.::.   |:.|.:.|.....:..|.:.|||.:||.|.:|...|.|::.
Worm    69 LSMNPTTPSEKSSSGEKGRYE---CEDCHEMFAVKRELATHMRIHSGEQPHSCTQCGKEFGTRQL 130

  Fly   292 LSSHSICHTGRMPCICEVCGRPCRDRGVLTAHMRRHTGERPAKCEVCGKAFYSFHDLNVHAVSHT 356
            |..|.:.|||....:|..|.:....:|.||.|:..|:|.||.:|..|.|.|....|||.|...|.
Worm   131 LKKHWMWHTGERSHVCPHCNKAFFQKGHLTQHLMIHSGGRPHECPQCHKTFIFKFDLNRHMKIHQ 195

  Fly   357 NLRPFVCDVCGSTFQRKKALRVHKLLHSEQRKYACKLCGK---------TFAQSGGLNAHMRSHD 412
            . |.|.|..||.:|.::..|..|.|        .||  ||         |.....||.:.:
Worm   196 E-RGFSCQQCGRSFLKQVMLDEHHL--------KCK--GKPSSPIRSLLTPTMKAGLESAI---- 245

  Fly   413 PARVKGAVKPLPQSVTIEVIEGKSPPTTTITMAIDLNVEEQ----------LVKQTE 459
                  ::||..:|:.:.       ..|...||..|.:::|          ||||.|
Worm   246 ------SIKPPQESMILS-------SETIAKMAQKLLIQQQENHRNALNTLLVKQHE 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	4/25 (16%)
		C2H2 Zn finger	251..271	CDD:275368	4/19 (21%)
		COG5048	<256..415	CDD:227381	51/167 (31%)
		zf-H2C2_2	263..288	CDD:290200	9/24 (38%)
		C2H2 Zn finger	279..327	CDD:275368	15/47 (32%)
		zf-H2C2_2	320..342	CDD:290200	10/21 (48%)
		C2H2 Zn finger	335..355	CDD:275368	8/19 (42%)
		C2H2 Zn finger	363..383	CDD:275368	7/19 (37%)
		zf-C2H2	389..411	CDD:278523	7/30 (23%)
		C2H2 Zn finger	391..411	CDD:275368	7/28 (25%)
M03D4.4	NP_001023313.1	C2H2 Zn finger	90..110	CDD:275368	4/19 (21%)
		zf-H2C2_2	102..127	CDD:290200	9/24 (38%)
		C2H2 Zn finger	118..138	CDD:275368	6/19 (32%)
		C2H2 Zn finger	146..166	CDD:275368	6/19 (32%)
		zf-H2C2_2	158..181	CDD:290200	10/22 (45%)
		zf-C2H2	172..194	CDD:278523	8/21 (38%)
		C2H2 Zn finger	174..194	CDD:275368	8/19 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000